James Cook vs. Lions - NFL - Player Props, Lines and Trends
16 September 2026
Ahead of Thursday's game, check out James Cook's player prop bet options. He'll hit the field at 8:15 p.m. ET on Amazon Prime Video. Cook and the Buffalo Bills (1-0) have a Week 2 matchup against the Detroit Lions (1-0) at New Highmark Stadium.
Keep reading for more Dunkel stats, insights and trends.James Cook Player Props
| Rush Yds Over/Under | Rush Yds Over Payout |
|---|---|
| 78.5 | -113 |
Cook Rushing Insights
- Thursday's rushing yards over/under for Cook is 78.5. That's 16.9 fewer yards than his average of 95.4 last season.
- In 11 of 17 games last year (64.7%) Cook racked up more than 78.5 rushing yards.
- Last season bookmakers set an average rushing yards over/under of 75.9 for Cook. He outpaced that, picking up 95.4 yards per game on the ground.
- Cook hit the over on his rushing yards total set by sportsbooks in nine of his 14 opportunities last year (64.3%).
- Cook had at least one rushing touchdown in eight games last year, including multiple rushing TDs four times.
Cook Receiving Insights
- Cook's average prop bet for receiving yards was an over/under of 13.9 last year. He put up 3.2 more yards per game than that average.
- Cook had a touchdown catch twice last year, out of 17 games played, but did not have multiple TD receptions in either of those games.
Detroit Lions Rankings (2025)
- In terms of defending against the run, the Lions were 14th in the NFL last year, allowing 114.5 yards per game.
- The Bills are up against the NFL's 16th-ranked D in terms of rushing TDs conceded last year (16).
For more expert NFL prop picks and best bets, visit Dunkel Index Best NFL Player Props today.
