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Mariners vs. Cardinals Dunkel MLB Picks, Predictions and Prop Bets - April 25

25 April 2026 By Data Skrive

The Seattle Mariners visit the St. Louis Cardinals at 2:15 p.m. ET on Saturday. Bryan Woo (1-2, 2.25 ERA) gets the start for the Mariners, who are 12-15 this season and fourth in the AL West. Matthew Liberatore (0-1, 3.67 ERA) is starting for the Cardinals, who are 14-11 and fourth in the NL Central.

Despite playing away from home the Mariners are at -148 to win, compared to the Cardinals at +124. The over/under for the Mariners-Cardinals game is set at 8.

Mariners vs. Cardinals Odds, Game Time

  • Game day: Saturday, April 25, 2026
  • Game time: 2:15 p.m. ET
  • Location: St. Louis, Missouri
  • Stadium: Busch Stadium
  • Favorite: Mariners (-148)
  • Underdog: Cardinals (+124)
  • Over/under: 8

How to Watch Mariners vs. Cardinals

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Mariners vs. Cardinals: Betting the Moneyline

  • The Mariners have been the moneyline favorite 23 total times this season. They've gone 11-12 in those games.
  • St. Louis has won in 12, or 54.5%, of the 22 contests it has been named as odds-on underdogs in this year.
  • Seattle is 7-5 this season when entering a game favored by -148 or more on the moneyline.
  • The Cardinals have a win-loss record of 2-3 when favored by +124 or worse by bookmakers this year.
  • The Mariners have a 59.7% chance to win this matchup based on the moneyline's implied probability.
  • Oddsmakers have implied with the moneyline set for this matchup that the Cardinals have a 44.6% chance of pulling out a win.

Mariners vs. Cardinals: Betting the Spread & Total

  • In the 27 games in which bookmakers have set an over/under for the Mariners, they have combined with opponents to go over the total 12 times (12-15-0).
  • St. Louis and its opponents have hit the over in 12 of its 25 games with a total this season.
  • The Mariners have a 9-18-0 record against the spread this season.
  • The Cardinals are 14-11-0 against the spread in their 25 games that had a posted line this season.
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