Mariners vs. Astros Dunkel MLB Picks, Predictions and Prop Bets - May 12

The Houston Astros will look to snap a three-game losing streak when hosting the Seattle Mariners at 8:10 p.m. ET on Tuesday. Bryan Woo (2-2, 4.02 ERA) gets the start for the Mariners, who are 20-22 this season and second in the AL West. Tatsuya Imai (1-0, 7.27 ERA) is starting for the Astros, who are 16-26 and fifth in the AL West.

The Mariners are currently a moderate moneyline favorite (-170) on the road at the Astros (+142). The contest has an over/under set at 8.5.

Mariners vs. Astros Odds, Game Time

• Game day: Tuesday, May 12, 2026
• Game time: 8:10 p.m. ET
• Location: Houston, Texas
• Stadium: Daikin Park
• Favorite: Mariners (-170)
• Underdog: Astros (+142)
• Over/under: 8.5

How to Watch Mariners vs. Astros

• TV Channel: SCHN and SEAM
• Live Stream: Fubo (Watch for free)

Bet now on FanDuel Sportsbook!

Mariners vs. Astros: Betting the Moneyline

• The Mariners have been favored on the moneyline 38 total times this season. They've gone 19-19 in those games.
• Houston has been underdogs in 26 games this season and has come away with the win 11 times (42.3%) in those contests.
• Seattle has entered seven games this season favored by -170 or more and is 4-3 in those contests.
• This season, the Astros have been victorious two times in six chances when named as an underdog of at least +142 or worse on the moneyline.
• Based on this matchup's moneyline, the Mariners have an implied win probability of 63%.
• The moneyline set for this matchup implies the Astros have a 41.3% chance of walking away with the win.

Mariners vs. Astros: Betting the Spread & Total

• In the 42 games in which oddsmakers have set an over/under for the Mariners, they have combined with opponents to go over the total 18 times (18-23-1).
• Games involving Houston have gone over the total set by bookmakers in 26 of 42 chances this season.
• The Mariners have a 15-27-0 record ATS this season (covering just 35.7% of the time).
• The Astros have posted a record of 16-26-0 against the spread this season.