Padres vs. Diamondbacks Dunkel MLB Picks, Predictions and Prop Bets - Sept. 27

Nolan Arenado carries a 12-game hitting streak into the Arizona Diamondbacks' game against the San Diego Padres, at 3:10 p.m. ET on Sunday, at Petco Park. Randy Vasquez (10-6, 4.01 ERA) will start for the Padres, who are 90-71 this season and second in the NL West. Mike Soroka (9-5, 3.31 ERA) is starting for the Diamondbacks, who are 86-75 and third in the NL West.

The Diamondbacks (+103) take their show on the road to face the favored Padres (-125). The contest has an over/under set at 7.5.

Padres vs. Diamondbacks Odds, Game Time

• Game day: Sunday, September 27, 2026
• Game time: 3:10 p.m. ET
• Location: San Diego, California
• Stadium: Petco Park
• Favorite: Padres (-125)
• Underdog: Diamondbacks (+103)
• Over/under: 7.5

How to Watch Padres vs. Diamondbacks

• TV Channel: SDPA and ARID
• Live Stream: Fubo (Watch for free)

Bet now on FanDuel Sportsbook!

Padres vs. Diamondbacks: Betting the Moneyline

• The Padres are 50-31 in games they were favored on the moneyline (winning 61.7% of those games).
• Arizona has been pegged as an underdog in 88 games this year and has walked away with the win 43 times (48.9%) in those games.
• San Diego is 36-23 this season when entering a game favored by -125 or more on the moneyline.
• The Diamondbacks have a mark of 28-35 in contests where bookmakers favor them by +103 or worse on the moneyline.
• Based on this matchup's moneyline, the Padres' implied win probability is 55.6%.
• The moneyline set for this matchup implies the Diamondbacks have a 49.3% chance of coming away with a victory in the contest.

Padres vs. Diamondbacks: Betting the Spread & Total

• The Padres have played in 161 games with over/under set, and have combined with opponents to go over the total 76 times (76-80-5).
• Arizona's games have gone over the total in 71 of its 161 chances.
• The Padres have a 91-70-0 record against the spread this season (covering 56.5% of the time).
• The Diamondbacks have an against the spread mark of 86-75-0 in 161 games with a line this season.