Pennsylvania vs. La Salle Dunkel Predictions & Vegas Odds - Nov. 29

The Pennsylvania Quakers (4-2) host the La Salle Explorers (3-4) at The Palestra, tipping off at 4:30 p.m. ET on Saturday, November 29, 2025. The Quakers are 3.5-point favorites in the game. The matchup has an over/under set at 149.5 points.

Pennsylvania enters this matchup on the heels of a 77-65 win against Merrimack on Friday. In Pennsylvania's win, Dalton Scantlebury led the way with a team-high 22 points (adding 13 rebounds and two assists). La Salle enters this matchup after a 63-58 loss to Hofstra on Friday. La Salle got a team-leading 13 points from Jerome Brewer Jr. in the loss.

Pennsylvania vs. La Salle Odds and Game Time

• When: Saturday, November 29, 2025 at 4:30 p.m. ET
• Where: The Palestra in Philadelphia, Pennsylvania
• Spread favorite: Pennsylvania -3.5
• Moneyline favorite: Pennsylvania -200
• Moneyline underdog: La Salle +164
• Over/Under: 149.5 points

How to watch Pennsylvania vs. La Salle

• TV Channel: ESPN+
• Check out the rest of our Dunkel Index NCAA Basketball Picks!

Betting the Over/Under: Pennsylvania vs. La Salle

• This season, Pennsylvania's games have hit the over on this game's 149.5-point total four times.
• This season, La Salle has played two games with a combined score higher than 149.5 points.
• The point total for the contest of 149.5 is 6.1 points fewer than the combined points per game averages for the Quakers (87.0) and Explorers (68.6).
• This game's total is 4.0 fewer points than the 145.5 these two teams combine to give up per game in 2024.
• This season, the average over/under for Pennsylvania's games is 165.2 points, 15.7 more than the total of 149.5 points set for this contest.
• La Salle's games have an average over/under of 135.9 points this season, 13.6 points lower than the over/under for this contest.

Betting the Spread: Pennsylvania vs. La Salle

• Against the spread, Pennsylvania is 3-2-0 this season.
• La Salle has covered the spread on two occasions this season.
• The Explorers have been underdogs by 3.5 points or more three times this year and have not covered the spread once.

Betting the Moneyline: Pennsylvania vs. La Salle

• Pennsylvania won the only game it has played as the moneyline favorite this season.
• The Quakers have not been a bigger favorite this season than the -200 moneyline set for this game.
• Pennsylvania has a 66.7% chance to win this game based on the implied probability of the moneyline.
• La Salle has been posted as the moneyline underdog four times this season but has yet walk away from any of those games with an upset.
• This season, the Explorers have been a moneyline underdog of -200 or more three times, losing every contest.
• La Salle has an implied victory probability of 37.9% according to the moneyline set for this matchup.