Oregon vs. Washington Dunkel NCAA Football Picks, Predictions and Odds - Nov. 29

The No. 5 Oregon Ducks (10-1) will test their eighth-ranked running game against the Washington Huskies (8-3), who have the No. 57 rush defense in college football, on Saturday, November 29, 2025. The Ducks are favored by 6.5 points in the contest.

The Ducks won versus the USC Trojans in their most recent game, 42-27.

Facing the UCLA Bruins in their last game, the Huskies won 48-14.

Oregon vs. Washington Predictions

For the upcoming game between the Oregon Ducks and Washington Huskies, computer-calculated against-the-spread, over/under, and score predictions are below, based on data from Dunkel Index.

• Pick ATS: Huskies (+ 6.5)
• Pick OU: Over (51.5)
  
• Prediction: Ducks 29 - Huskies 28

Bet now on FanDuel Sportsbook!

Oregon vs. Washington Moneylines

Snag a peek below at the most up-to-date moneylines for the Ducks-Huskies matchup.

• Oregon Moneyline: -268
• Washington Moneyline: +218

Pick with the best in the business! Get free picks for every game, every week at the Dunkel Index.

Oregon Betting Insights

• Oregon has won 88.9% of the games this season when it was favored on the moneyline (8-1).
• Oregon is 7-1 (winning 87.5% of its games) when playing as a moneyline favorite of -268 or shorter.
• The Ducks and their opponents have combined to score more than 51.5 points in six of 11 games this season.
• The average point total in Ducks contests this year is 52.4, 0.9 more points than this game's over/under.
• The Ducks are the ninth-highest scoring team in college football this year. The Huskies have scored the 19th-most points.

Washington Betting Insights

• Washington has lost both games it has played as underdogs this season.
• Washington has played as an underdog of +218 or more once this season and lost that game.
• Washington has played six games this season that have gone over 51.5 combined points scored.
• Washington's matchups this season have a 52.3-point average over/under, 0.8 more points than this game's total.

Watch Oregon vs. Washington on Fubo.

Key Stats for Oregon vs. Washington

• Washington owns a 3-2 record against Oregon in their last five matchups.
• The two teams have gone over the total on two occasions while sharing a split 2-2-1 record in their matchups against the spread.
• The Ducks have been a difficult matchup for opposing teams, as they rank top-25 in both total offense (12th-best with 471.8 yards per game) and total defense (third-best with 248.7 yards allowed per game) this season.
• Oregon has been clicking on all fronts this year, as they rank eighth-best in scoring offense (39.3 points per game) and eighth-best in scoring defense (14.9 points allowed per game).
• The Huskies' defense has been leading the charge for the team, as they rank 18th-best in the FBS with 304.0 total yards ceded per game. In terms of offense, they are putting up 426.5 total yards per game, which ranks 30th.
• Washington has been a top-25 unit on both sides of the ball this season, as it ranks 19th-best in points per game (35.5) and 19th-best in points surrendered per game (18.8).