Patriots vs. Saints Week 6 Dunkel NFL Picks, Predictions and Odds

The New England Patriots (3-2) are considered favorites (-3.5) according to the bookmakers ahead of their game versus the New Orleans Saints (1-4) on October 12, 2025, starting at 1 p.m. ET, airing on CBS. An over/under of 46.5 points has been set for the matchup.

The Patriots are putting up 336.6 yards per game on offense this year (16th in NFL), and they are surrendering 327.8 yards per game (18th) on defense. From an offensive standpoint, the Saints are putting up 307.2 total yards per contest (24th-ranked). They rank 17th in the NFL on defense (326.2 total yards surrendered per game).

Patriots vs. Saints Odds and Game Time

• Date: Sunday, October 12, 2025
• Time: 1 p.m. ET
• City: New Orleans, Louisiana
• Venue: Caesars Superdome
• Total: 46.5 points
• Spread: Patriots -3.5
• Moneyline: Patriots (-198), Saints (+164)

How to watch Patriots vs. Saints

• TV Channel: CBS (KLFY-Lafayette, LA)
• Live Stream: Fubo

Betting the Over/Under: Patriots vs. Saints

• Patriots games have had a combined total of more than 46.5 points two times this season (in five outings).
• New England games have hit the over twice this season.
• The Saints have played three games this season that have gone over 46.5 combined points scored.
• So far this year, three of New Orleans' five games with a set number have hit the over.
• The two teams combine to score 43.4 points per game, 3.1 fewer points than this matchup's total.
• These teams give up 47.2 points per game combined, 0.7 more points than this matchup's total.

Betting the Spread: Patriots vs. Saints

• New England has put together a 3-2-0 ATS record so far this year.
• New England has won their only game this season when playing as at least 3.5-point favorites.
• The Saints have won two games against the spread this year.
• New Orleans has been an underdog by 3.5 points or more three times this year, and covered the spread in one of those matchups.
• The Saints have one win against the spread, and are 1-2 overall, at home this season.
• New Orleans is winless ATS (0-1) as 3.5-point underdogs or greater at home.

Betting the Moneyline: Patriots vs. Saints

• New England has been the moneyline favorite only two other times so far this season, and they split the two games.
• The Saints have been the underdog in four games this season, and they have failed to win any of those contests.
• New England has played as a moneyline favorite of -198 or shorter in just one game this season, which it won.
• This season, New Orleans has been at least a +164 underdog on the moneyline three times, losing each of those contests.
• Based on this matchup's moneyline, the Patriots have an implied win probability of 66.4%.

Dunkel Prediction for Patriots vs. Saints

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