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Brewers vs. Cardinals Dunkel MLB Picks, Predictions and Prop Bets - Sept. 27

27 September 2026 By Data Skrive

The St. Louis Cardinals will look to Alec Burleson, riding a three-game homer streak, against the Milwaukee Brewers at 3:10 p.m. ET on Sunday, at American Family Field. Jacob Misiorowski (15-5, 1.86 ERA) gets the start for the Brewers, who are 102-59 this season and first in the NL Central. Andre Pallante (12-8, 3.61 ERA) is expected to start for the Cardinals, who are 77-84 and fourth in the NL Central.

The Cardinals (+173) are on the road versus the favored Brewers (-212). The game's total is set at 7.

Brewers vs. Cardinals Odds, Game Time

  • Game day: Sunday, September 27, 2026
  • Game time: 3:10 p.m. ET
  • Location: Milwaukee, Wisconsin
  • Stadium: American Family Field
  • Favorite: Brewers (-212)
  • Underdog: Cardinals (+173)
  • Over/under: 7

How to Watch Brewers vs. Cardinals

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Brewers vs. Cardinals: Betting the Moneyline

  • The Brewers have been the moneyline favorite 125 total times this season. They've gone 83-42 in those games.
  • St. Louis has come away with 50 wins in the 108 contests it has been listed as the underdogs in this season.
  • Milwaukee has entered 19 games this season favored by -212 or more and is 15-4 in those contests.
  • The Cardinals have a win-loss record of 3-7 when favored by +173 or worse by sportsbooks this year.
  • The Brewers have an implied moneyline win probability of 67.9% in this contest.
  • The Cardinals have an implied victory probability of 36.6% according to the moneyline set for this matchup.

Brewers vs. Cardinals: Betting the Spread & Total

  • The Brewers have played in 161 games with set over/under, and have combined with opponents to go over the total 71 times (71-84-6).
  • St. Louis and its opponents have hit the over in 71 of its 161 games with a total this season.
  • The Brewers have an 83-78-0 record against the spread this season.
  • The Cardinals have an against the spread record of 88-73-0 in 161 games with a line this season.
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