Memphis vs. Southern Illinois Dunkel Predictions & Vegas Odds - Nov. 26

The Memphis Tigers (1-4) host the Southern Illinois Salukis (3-3) at FedExForum, beginning at 8 p.m. ET on Wednesday, November 26, 2025. The Salukis are 10.5-point underdogs in the game. The point total is 157.5 in the matchup.

Memphis enters this contest after a 69-68 loss to Wake Forest on Friday. In the losing effort, Dug McDaniel paced Memphis with 24 points. Southern Illinois' last game on Monday ended in an 81-73 loss to UAB. Quel'Ron House totaled 18 points, one rebound and one assist for Southern Illinois.

Memphis vs. Southern Illinois Odds and Game Time

• When: Wednesday, November 26, 2025 at 8 p.m. ET
• Where: FedExForum in Memphis, Tennessee
• Spread favorite: Memphis -10.5
• Moneyline favorite: Memphis -621
• Moneyline underdog: Southern Illinois +448
• Over/Under: 157.5 points

How to watch Memphis vs. Southern Illinois

• TV Channel: ESPN+
• Check out the rest of our Dunkel Index NCAA Basketball Picks!

Betting the Over/Under: Memphis vs. Southern Illinois

• This season, Memphis' games have hit the over on this game's 157.5-point total twice.
• This season, three games Southern Illinois has played finished with a combined score higher than 157.5 points.
• The point total for the matchup of 157.5 is 0.2 points fewer than the combined points per game averages for the Tigers (74 points per game) and the Salukis (83.7 points per game).
• The 151.8 points per game these two teams surrender to opponents combined this season are 5.7 less than the 157.5-point total in this contest.
• This season the average over/under for Memphis' games is 152.8 points, 4.7 lower than the over/under of 157.5 points set for this contest.
• Southern Illinois' games have an average over/under of 156.7 points this season, 0.8 fewer points than the over/under for this contest.

Betting the Spread: Memphis vs. Southern Illinois

• In Memphis' five games this year, it has four wins against the spread.
• Southern Illinois has three wins against the spread in five games this year.
• The Salukis covered the spread in their only game when underdogs by 10.5 points or more.

Betting the Moneyline: Memphis vs. Southern Illinois

• Memphis has split the two games it has played as a moneyline favorite this season.
• The Tigers have not been a bigger favorite this season than the -621 moneyline set for this game.
• The moneyline for this contest implies a 86.1% chance of a victory for Memphis.
• Southern Illinois has been moneyline underdogs in three games this season, however, it has failed to come away with a win in any of those games.
• The Salukis have played as an underdog of +448 or more just one time this year and came away with a loss in that game.
• Southern Illinois has an implied victory probability of 18.2% according to the moneyline set by oddsmakers for this matchup.