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Rams vs. Panthers Week 13 Dunkel NFL Picks, Predictions and Odds

25 November 2025 By Data Skrive

The Los Angeles Rams (9-2) are big favorites (-10.5) over the Carolina Panthers (6-6). The Rams have won six games straight. An over/under of 45.5 points has been established for the matchup.

The Rams rank sixth in points scored this year (27.8 points per game), but they've been thriving on the defensive side of the ball, ranking best in the NFL with 16.3 points allowed per game. The Panthers rank fifth-worst in points per game (18.0), but they've been better on the defensive side of the ball, ranking 13th in the NFL with 22.4 points surrendered per contest.

Rams vs. Panthers Odds and Game Time

  • Date: Sunday, November 30, 2025
  • Time: 1 p.m. ET
  • City: Charlotte, North Carolina
  • Venue: Bank of America Stadium
  • Total: 45.5 points
  • Spread: Rams -10.5
  • Moneyline: Rams (-649), Panthers (+470)

How to watch Rams vs. Panthers

  • TV Channel: FOX (KSCC-Corpus Christi, TX)
  • Live Stream: Fubo

Betting the Over/Under: Rams vs. Panthers

  • The Rams and their opponents have scored more than 45.5 total points five times this season.
  • So far this season, four of Los Angeles' 11 games have hit the over.
  • The Panthers have combined with their opponent to score more than 45.5 points in six of 12 games this season.
  • In Carolina's 12 contests this year, the combined scoring has gone over the point total six times.
  • These two teams score 45.8 points per game combined, 0.3 more than this game's point total.
  • These two teams surrender a combined 38.7 points per game, 6.8 fewer points than this contest's total.

Betting the Spread: Rams vs. Panthers

  • Los Angeles has put together an 8-3-0 record against the spread this season.
  • Los Angeles has been favored by 10.5 points or more once this season, and covered the spread.
  • The Panthers have compiled a 7-5-0 ATS record so far this year.
  • Carolina has covered the spread when playing as at least 10.5-point underdogs in its only opportunity this season.
  • The Panthers are 3-2 against the spread, and 3-2 overall, at home this season.
  • The Rams are 4-1 overall, and 4-1 against the spread, away from home.
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Betting the Moneyline: Rams vs. Panthers

  • Los Angeles is 9-1 in games they were favored on the moneyline (winning 90% of those games).
  • This season, the Panthers have won six out of the 11 games, or 54.5%, in which they've been the underdog.
  • Los Angeles has played as a moneyline favorite of -649 or shorter in only one game this season, which it won.
  • Carolina has played as an underdog of +470 or more once this season and won that game.
  • Based on this game's moneyline, the Rams' implied win probability is 86.6%.

Dunkel Prediction for Rams vs. Panthers

ATS Over/Under Score Prediction
Panthers (+10.5) Over (45.5) Rams 29 - Panthers 22

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