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Rams vs. Cardinals Week 18 Dunkel NFL Picks, Predictions and Odds

30 December 2025 By Data Skrive

Having lost two in a row, the Arizona Cardinals (3-13) will take on the Los Angeles Rams (11-5). The Rams are heavy favorites, expected to win by two touchdowns or more (currently -14.5). The expected point total for the matchup is set at 48.5.

The Rams rank eighth in scoring defense this year (20.4 points allowed per game), but they've been thriving on the offensive side of the ball, ranking best in the NFL with 30.1 points per game. The Cardinals have been sputtering on defense, ranking fourth-worst with 28.2 points given up per game. They have been better on the other side of the ball, regstering 20.9 points per contest (23rd-ranked).

Rams vs. Cardinals Odds and Game Time

  • Date: Sunday, January 4, 2026
  • Time: 4:25 p.m. ET
  • City: Inglewood, California
  • Venue: SoFi Stadium
  • Total: 48.5 points
  • Spread: Rams -14.5
  • Moneyline: Rams (-1205), Cardinals (+750)

How to watch Rams vs. Cardinals

  • TV Channel: FOX (KRXI- Reno, NV)
  • Live Stream: Fubo

Betting the Over/Under: Rams vs. Cardinals

  • Rams games this season have featured more combined points than this contest's total of 48.5 points nine times.
  • So far this season, nine of Los Angeles' 16 games have hit the over.
  • The Cardinals and their opponents have combined to score more than 48.5 points in nine of 16 games this season.
  • Arizona games have gone over the point total nine out of 16 times this year.
  • The two teams combine to score 51 points per game, 2.5 more points than this matchup's total.
  • Opponents of these teams score 48.6 points per game combined, 0.1 more points than this contest's total.

Betting the Spread: Rams vs. Cardinals

  • Los Angeles has compiled an 11-5-0 record against the spread this season.
  • Los Angeles has been favored by 14.5 points or more once this season, and covered the spread.
  • The Cardinals have put together a 6-10-0 ATS record so far this year.
  • At home this season, the Rams are 6-1 overall and 5-2 against the spread.
  • At home, as 14.5-point favorites or greater, Los Angeles is unbeaten ATS (1-0).
  • This season in away games, the Cardinals are 5-3 against the spread and 2-6 overall.
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Betting the Moneyline: Rams vs. Cardinals

  • Los Angeles is 11-3 in games they were favored on the moneyline (winning 78.6% of those games).
  • This season, the Cardinals have been the underdog 13 times and won one of those games.
  • Los Angeles has played as a moneyline favorite of -1205 or shorter in only one game this season, which it won.
  • Arizona has not been a bigger underdog this season than the +750 moneyline set for this game.
  • Based on this contest's moneyline, the Rams have an implied win probability of 92.3%.

Dunkel Prediction for Rams vs. Cardinals

ATS Over/Under Score Prediction
Cardinals (+14.5) Under (48.5) Rams 23 - Cardinals 19

For more expert NFL picks, visit our Dunkel Index NFL Picks and Predictions.

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