Iowa State vs. Creighton Dunkel Predictions & Vegas Odds - Nov. 25

The No. 15 Iowa State Cyclones (5-0) visit the Creighton Bluejays (3-2) at Michelob ULTRA Arena, starting at 2 p.m. ET on Tuesday, November 25, 2025. The Bluejays are 8.5-point underdogs in the game. The matchup has an over/under of 151.5.

Their last time out, Iowa State won on Monday 83-82 over St. John's. Milan Momcilovic's team-leading 23 points led Iowa State in the victory. Creighton is coming off of an 81-74 loss to Baylor in its last outing on Monday. Hudson Greer put up 16 points, three rebounds and zero assists for Creighton.

Iowa State vs. Creighton Odds and Game Time

• When: Tuesday, November 25, 2025 at 2 p.m. ET
• Where: Michelob ULTRA Arena in Las Vegas, Nevada
• Spread favorite: Iowa State -8.5
• Moneyline favorite: Iowa State -437
• Moneyline underdog: Creighton +337
• Over/Under: 151.5 points

How to watch Iowa State vs. Creighton

• TV Channel: truTV
• Check out the rest of our Dunkel Index NCAA Basketball Picks!

Betting the Over/Under: Iowa State vs. Creighton

• This season, Iowa State and its opponents have combined to outscore Tuesday's over/under of 151.5 points four times.
• Three of Creighton's games have ended with a combined score higher than 151.5 points this season.
• Together, the two teams combine for 170.6 points per game, 19.1 points more than the total of 151.5 for this contest.
• These two teams surrender a combined 136.6 points per game, 14.9 less than this contest's over/under.
• On average, Iowa State has had a 159.2-point over/under in its games this season, 7.7 more points than the over/under in this matchup.
• The over/under for this matchup is 3.5 points more than the average over/under in Creighton's games this season (148 points).

Betting the Spread: Iowa State vs. Creighton

• Iowa State has played five games, with three wins against the spread.
• The Cyclones have covered the spread twice this season when favored by 8.5 points or more (in three chances).
• So far this year Creighton has one win against the spread.
• The Bluejays have been underdogs by 8.5 points or more one time this season and have not covered the spread once.
• Creighton has one win against the spread, and is 3-0 overall, at home this year.
• At home, as a 8.5-point underdog or more, Creighton has one win ATS (1-2).

Betting the Moneyline: Iowa State vs. Creighton

• Iowa State has been listed as the moneyline favorite three times this season and has won all of those games.
• The Cyclones have played as a favorite of -437 or more once this season and won that game.
• The bookmakers' moneyline implies a 81.4% chance of a victory for Iowa State.
• Creighton was defeated in both of the games it has played as moneyline underdogs this season.
• The Bluejays have played as an underdog of +337 or more just one time this year and came away with a loss in that game.
• Creighton has an implied victory probability of 22.9% according to the moneyline set by oddsmakers for this matchup.