Illinois vs. Missouri Dunkel Predictions & Vegas Odds - Dec. 22

The No. 18 Illinois Fighting Illini (8-3) visit the Missouri Tigers (10-2) at Enterprise Center, beginning at 8 p.m. ET on Monday, December 22, 2025. The Tigers are 8.5-point underdogs in the game. The over/under in the matchup is set at 155.5.

Illinois fell in its last matchup 83-80 against Nebraska on Saturday. In Illinois' loss, Kylan Boswell led the way with a team-high 20 points (adding three rebounds and three assists). Missouri enters this contest after an 82-60 win over Bethune-Cookman on Sunday. Jacob Crews put up 20 points, five rebounds and one assist for Missouri.

Illinois vs. Missouri Odds and Game Time

• When: Monday, December 22, 2025 at 8 p.m. ET
• Where: Enterprise Center in St. Louis, Missouri
• Spread favorite: Illinois -8.5
• Moneyline favorite: Illinois -394
• Moneyline underdog: Missouri +310
• Over/Under: 155.5 points

How to watch Illinois vs. Missouri

• TV Channel: FOX Sports 2
• Live Stream: Fubo
• Check out the rest of our Dunkel Index NCAA Basketball Picks!

Betting the Over/Under: Illinois vs. Missouri

• Eight of Illinois' games this season have gone over Monday's total of 155.5 points.
• There have been six Missouri games that ended with a combined score higher than 155.5 points this season.
• Together, the two teams combine for 174.6 points per game, 19.1 points more than the over/under of 155.5 for this game.
• These two teams give up a combined 141.3 points per game, 14.2 points less than this contest's over/under.
• Illinois has a 159.4 average over/under in its games this season, 3.9 more points than the over/under in this matchup.
• A difference of 1.1 points separates the average over/under in Missouri's games (156.6 points) and this contest's over/under (155.5).

Betting the Spread: Illinois vs. Missouri

• Illinois is 6-5-0 against the spread this season.
• This season, the Fighting Illini have an ATS record of 3-3 in their six games as a favorite of 8.5 points or more.
• In Missouri's 12 games this season, it has five wins against the spread.
• At home this season, Missouri is 9-0 overall and 4-5 against the spread.
• As a 8.5-point underdog or greater at home, Missouri is 3-5 ATS.

Betting the Moneyline: Illinois vs. Missouri

• This season, Illinois has won seven out of the nine games in which it has been the moneyline favorite.
• The Fighting Illini have entered six games this season favored by -394 or more and are 5-1 in those contests.
• Illinois has a 79.8% chance to win this game based on the implied probability of the moneyline.
• Missouri was defeated in the one game it played as the moneyline underdog this season.
• This is the worst odds of a win that sportsbooks have given the Tigers this season with a +310 moneyline set for this game.
• Oddsmakers have implied with the moneyline set for this matchup that Missouri has a 24.4% chance of pulling out a win.