Astros vs. White Sox Game 2 of the AL Wild Card Series Dunkel MLB Picks, Predictions and Props - Sept. 30

The Houston Astros are at home for Game 2 of the AL Wild Card Series versus the Chicago White Sox, Wednesday at 5 p.m. ET. The White Sox have a 1-0 series lead as they try to move on to the ALDS. Hunter Brown (6-4, 3.19 ERA) gets the start for the Astros, and Sean Burke (11-7, 3.34 ERA) is expected to start for the White Sox.

The sportsbooks have spoken, making the Astros (-153) a moderate moneyline favorite to defeat the White Sox (+126) at home. The contest has an over/under set at 7.5.

Astros vs. White Sox Odds, Game Time

• Game day: Wednesday, September 30, 2026
• Game time: 5 p.m. ET
• Location: Houston, Texas
• Stadium: Daikin Park
• Favorite: Astros (-153)
• Underdog: White Sox (+126)
• Over/under: 7.5

How to Watch Astros vs. White Sox

• TV Channel: NBCSN and Peacock
• Live Stream: Fubo (Watch for free)

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Astros vs. White Sox: Betting the Moneyline

• The Astros have put together a 36-36 record in games they were listed as the moneyline favorite (winning 50% of those games).
• Chicago has been victorious in 54, or 49.5%, of the 109 contests it has been chosen as underdogs in this season.
• This season Houston has won 11 of its 26 games, or 42.3%, when favored by at least -153 on the moneyline.
• This season, the White Sox have been victorious 16 times in 40 chances when named as an underdog of at least +126 or longer on the moneyline.
• The Astros have a 60.5% chance to win this matchup based on the moneyline's implied probability.
• The White Sox have an implied victory probability of 44.2% according to the moneyline set by sportsbooks for this matchup.

Astros vs. White Sox: Betting the Spread & Total

• The Astros have played in 163 games with set over/under, and have combined with opponents to go over the total 80 times (80-73-10).
• Chicago and its opponents have hit the over in 94 of its 163 games with a total this season.
• The Astros have covered 52.1% of their games this season, going 85-78-0 ATS.
• In 163 games with a line this season, the White Sox have a mark of 94-69-0 against the spread.