Astros vs. Athletics Dunkel MLB Picks, Predictions and Prop Bets - Sept. 27

Jeremy Pena leads the Houston Astros into a matchup against the Athletics a game after homering twice in a 13-2 victory over the Athletics. It starts at 3:05 p.m. ET on Sunday. Peter Lambert (8-10, 3.87 ERA) gets the start for the Astros, who are 80-81 this season and first in the AL West. Seth Johnson (1-0, 6.19 ERA) is the expected starter for the Athletics, who are 64-97 and fourth in the AL West.

Bookmakers have set the Astros as the moderate moneyline favorites (-171) on the road versus the Athletics (+140). The over/under for this contest is 10.

Astros vs. Athletics Odds, Game Time

• Game day: Sunday, September 27, 2026
• Game time: 3:05 p.m. ET
• Location: West Sacramento, California
• Stadium: Sutter Health Park
• Favorite: Astros (-171)
• Underdog: Athletics (+140)
• Over/under: 10

How to Watch Astros vs. Athletics

• TV Channel: NBCS-CA and SCHN
• Live Stream: Fubo (Watch for free)

Bet now on FanDuel Sportsbook!

Astros vs. Athletics: Betting the Moneyline

• The Astros have won 50% of the games this season when they were the moneyline favorite (35-35).
• The Athletics have been underdogs in 125 games this season and have come away with the win 48 times (38.4%) in those contests.
• The Astros have a record of 6-8, a 42.9% win rate, when they're favored by -171 or more by oddsmakers this season.
• This season, the Athletics have come away with a win 13 times in 49 chances when named as an underdog of at least +140 or worse on the moneyline.
• The Astros have an implied moneyline win probability of 63.1% in this contest.
• Bookmakers have implied with the moneyline set for this matchup that the Athletics have a 41.7% chance of pulling out a win.

Astros vs. Athletics: Betting the Spread & Total

• The Astros have played in 161 games with an over/under set, and have combined with their opponents to go over the total 79 times (79-72-10).
• The Athletics and their opponents have hit the over in 84 of their 161 games with a total this season.
• The Astros have an 84-77-0 record against the spread this season (covering 52.2% of the time).
• The Athletics are 77-84-0 against the spread in their 161 games with a line set by sportsbooks this season.