DePaul vs. Detroit Mercy Dunkel Predictions & Vegas Odds - Nov. 23

The DePaul Blue Demons (3-2) face the Detroit Mercy Titans (1-5) as 16.5-point favorites on Sunday, November 23, 2025 at 6 p.m. ET on ESPN+. The matchup has an over/under of 147.5 points.

DePaul won its most recent matchup 93-62 against Gardner-Webb on Tuesday. In the win, CJ Gunn paced DePaul with 18 points. Detroit Mercy's last contest on Friday ended in an 84-56 loss to Michigan State. Detroit Mercy got a team-leading 14 points from Orlando Lovejoy in the loss.

DePaul vs. Detroit Mercy Odds and Game Time

• When: Sunday, November 23, 2025 at 6 p.m. ET
• Where: Wintrust Arena in Chicago, Illinois
• Spread favorite: DePaul -16.5
• Moneyline favorite: DePaul -3030
• Moneyline underdog: Detroit Mercy +1200
• Over/Under: 147.5 points

How to watch DePaul vs. Detroit Mercy

• TV Channel: ESPN+
• Check out the rest of our Dunkel Index NCAA Basketball Picks!

Betting the Over/Under: DePaul vs. Detroit Mercy

• DePaul and its opponents have combined to outscore Sunday's total of 147.5 points three times this season.
• This season, three of Detroit Mercy's games have ended with a combined score higher than 147.5 points.
• Together, the two teams combine for 150.1 points per game, 2.6 points more than the point total of 147.5 for this contest.
• These two teams give up a combined 149.2 points per game, 1.7 more than this contest's over/under.
• This season the average over/under for DePaul's games is 144.8 points, 2.7 lower than the over/under of 147.5 points set for this contest.
• Detroit Mercy's games have an average over/under of 154.5 points this season, 7.0 more points than the over/under for this game.

Betting the Spread: DePaul vs. Detroit Mercy

• DePaul is 3-2-0 against the spread this year.
• The Blue Demons have been favored by 16.5 points or more four times this season and have covered the spread in two of them.
• Detroit Mercy has covered the spread twice this year.
• This season, the Titans have one ATS win in two games as an underdog of 16.5 points or more.
• At home this season, DePaul is 3-2 against the spread and 3-2 overall.
• At home, DePaul has two wins ATS (2-2) as a 16.5-point favorite or more.
• In away games, Detroit Mercy has two wins against the spread and are 0-4 overall.

Betting the Moneyline: DePaul vs. Detroit Mercy

• DePaul has entered the game as moneyline favorites four times this season and won three of those games.
• The Blue Demons are 3-1 this season when entering a game favored by -3030 or more on the moneyline.
• The implied probability of a win from DePaul, based on the moneyline, is 96.8%.
• Detroit Mercy has been named as the moneyline underdog four times this season but has yet to come away with a victory in any of those games.
• The Titans have been listed as an underdog of +1200 or more on two occasions this season and lost both games.
• Detroit Mercy has an implied victory probability of 7.7% according to the moneyline set by oddsmakers for this matchup.