Guardians vs. Athletics Dunkel MLB Picks, Predictions and Prop Bets - Sept. 19

The Athletics bring a four-game losing streak into a home matchup versus the Cleveland Guardians, at 6:10 p.m. ET on Saturday. Tanner Bibee (6-15, 4.16 ERA) gets the start for the Guardians, who are 79-75 this season and first in the AL Central. Jacob Lopez (6-4, 5.02 ERA) is the expected starter for the Athletics, who are 61-93 and fourth in the AL West.

Bookmakers have made the Guardians a decent moneyline favorite (-186) at home over the Athletics (+151). The over/under for the Guardians-Athletics game is 7.5.

Guardians vs. Athletics Odds, Game Time

• Game day: Saturday, September 19, 2026
• Game time: 6:10 p.m. ET
• Location: Cleveland, Ohio
• Stadium: Progressive Field
• Favorite: Guardians (-186)
• Underdog: Athletics (+151)
• Over/under: 7.5

How to Watch Guardians vs. Athletics

• TV Channel: CLEG and NBCS-CA
• Live Stream: Fubo (Watch for free)

Bet now on FanDuel Sportsbook!

Guardians vs. Athletics: Betting the Moneyline

• The Guardians have been the moneyline favorite 96 total times this season. They've finished 51-45 in those games.
• The Athletics have been chosen as underdogs in 118 games this year and have walked away with the win 45 times (38.1%) in those games.
• This season, the Guardians have won five of their six games when favored by at least -186 on the moneyline.
• This year, the Athletics have won 10 of 33 games when listed as at least +151 or better on the moneyline.
• The implied moneyline probablility for this matchup gives the Guardians a 65% chance to win.
• The moneyline set for this matchup implies the Athletics have a 39.8% chance of coming away with a victory in the contest.

Guardians vs. Athletics: Betting the Spread & Total

• The Guardians have played in 154 games with a set over/under, and have combined with their opponents to go over the total 74 times (74-78-2).
• The Athletics and their opponents have hit the over in 78 of their 154 games with a total this season.
• The Guardians have covered 47.4% of their games this season, going 73-81-0 against the spread.
• The Athletics have an against the spread record of 73-81-0 in 154 games with a line this season.