Buffalo vs. Akron Dunkel NCAA Football Picks, Predictions and Odds - Oct. 25

The Buffalo Bulls (4-3) host the Akron Zips (2-6) on Saturday, October 25, 2025 in a matchup between MAC rivals at UB Stadium. Akron is a 10-point underdog.

In their most recent game, the Bulls won versus the UMass Minutemen, 28-21.

Last time around, the Zips fell to the Ball State Cardinals, with 42-28 being the final score.

Buffalo vs. Akron Predictions

For the upcoming contest between the Buffalo Bulls and Akron Zips, computer-calculated against-the-spread, over/under, and score predictions are below, sourced from Dunkel Index.

• Pick ATS: Zips (+ 10)
• Pick OU: Under (49.5)
  
• Prediction: Zips 21 - Bulls 20

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Buffalo vs. Akron Moneylines

Grab a look below at the most recent moneylines for the Bulls-Zips game.

• Buffalo Moneyline: -377
• Akron Moneyline: +296

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Buffalo Betting Insights

• Buffalo has gone 4-1 in games it was favored on the moneyline (winning 80% of those games).
• Buffalo has played in three games as a moneyline favorite with odds of -377 or shorter and won them all.
• Bulls games this season have gone over this contest's total of 49.5 points three times.
• The average total in Bulls matchups this year is 48.1, 1.4 fewer points than this game's over/under.
• The Zips are college football's 114th-highest scoring team this season compared to the 89th-ranked Bulls.

Akron Betting Insights

• This season, Akron has won one out of the six games in which it has been the underdog.
• Akron has not won as an underdog of +296 or more on the moneyline this season in four such games.
• Akron games this season have had a combined scoring total higher than 49.5 points in five of eight outings.
• Akron has had an average of 49.1 points scored in their games so far this season, 0.4 points fewer than this game's over/under.

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Key Stats for Buffalo vs. Akron

• In their past four head-to-head bouts, Buffalo has defeated Akron four times.
• In those games against Akron, the Bulls have covered three times while outscoring the total on one occasion.
• The Bulls are averaging 370 yards per game on offense (82nd in the FBS), and they rank 45th on the other side of the ball with 339.7 yards allowed per game.
• Buffalo is compiling 25.6 points per game on offense (86th in the FBS), and ranks 44th on defense with 21.3 points allowed per game.
• The Zips have lots of room to improve, as they rank 21st-worst in total yards per game (326.5) and 15th-worst in total yards allowed per game (431).
• Akron's offense has been a bottom-25 unit this season, posting 18.1 points per game, which ranks 11th-worst in the FBS. On the defensive side of the ball, it ranks 111th with 30.6 points ceded per contest.