Xavier vs. Creighton Dunkel Predictions & Vegas Odds - Dec. 17

The Xavier Musketeers (8-3, 0-0 Big East) host the Creighton Bluejays (5-5, 0-0 Big East) at Cintas Center, tipping off at 6:30 p.m. ET on Wednesday, December 17, 2025. The Musketeers are 2.5-point favorites in the game. The over/under for the matchup is set at 149.5.

Xavier took care of business in its last outing 75-57 against Missouri State on Friday. In Xavier's win, Jovan Milicevic led the way with a team-high 17 points (adding seven rebounds and two assists). Creighton's last contest on Saturday ended in an 83-76 loss to Kansas State. Isaac Traudt scored a team-best 18 points for Creighton in the loss.

Xavier vs. Creighton Odds and Game Time

• When: Wednesday, December 17, 2025 at 6:30 p.m. ET
• Where: Cintas Center in Cincinnati, Ohio
• Spread favorite: Xavier -2.5
• Moneyline favorite: Xavier -157
• Moneyline underdog: Creighton +130
• Over/Under: 149.5 points

How to watch Xavier vs. Creighton

• TV Channel: FOX Sports 1
• Live Stream: Fubo
• Check out the rest of our Dunkel Index NCAA Basketball Picks!

Betting the Over/Under: Xavier vs. Creighton

• This season, Xavier and its opponents have combined to outscore Wednesday's total of 149.5 points six times.
• Five of Creighton's games have ended with a combined score higher than 149.5 points this season.
• The over/under for the contest of 149.5 is 3.5 points fewer than the combined points per game averages for the Musketeers (78.4) and Bluejays (74.6).
• These two teams surrender a combined 144.1 points per game, 5.4 less than this contest's over/under.
• Xavier has seen a 149.8 average over/under in its games this season, 0.3 points more than the over/under in this contest.
• Creighton's games have an average over/under of 147.2 points this season, 2.3 fewer points than the over/under for this game.

Betting the Spread: Xavier vs. Creighton

• In Xavier's 11 games this season, it has six wins against the spread.
• The Musketeers have an against the spread record of 3-4 in their seven games as a favorite of 2.5 points or more so far this season.
• Creighton is 3-7-0 against the spread this season.
• This year, the Bluejays are winless against the spread when entering a game as an underdog of 2.5 points or more (in four chances).
• Xavier is 4-4 against the spread, and 7-1 overall, at home.
• This season, as a 2.5-point favorite or more at home, Xavier is 3-4 ATS.

Betting the Moneyline: Xavier vs. Creighton

• This season, Xavier has won seven out of the eight games in which it has been the moneyline favorite.
• The Musketeers have a record of 6-1 when favored by -157 or more by oddsmakers this season.
• The bookmakers' moneyline implies a 61.1% chance of a victory for Xavier.
• Creighton has been named as the moneyline underdog four times this season but has yet to come away with a victory in any of those games.
• The Bluejays have yet to win this season when listed as an underdog of +130 or worse on the moneyline this season.
• The moneyline set for this matchup implies Creighton has a 43.5% chance of walking away with the win.