NFL Predictions & Betting Odds - Week 15
09 December 2025

The matchups in a Week 15 NFL lineup that shouldn't be missed include the Detroit Lions playing the Los Angeles Rams at SoFi Stadium.
We've got you covered with a quick rundown on every NFL tilt this week with over/unders, spreads, moneylines, and Dunkel Index predictions. Keep reading for the key information.
Bet now on FanDuel Sportsbook!Week 15 Games, Betting Info, and Predictions
There are 16 games on the pro football schedule this week. Here's a peek at each matchup:
Atlanta Falcons (5-9) at Tampa Bay Buccaneers (7-7)
- Game Time: 8:15 p.m. ET | Thursday, December 11, 2025
- Venue: Raymond James Stadium (Tampa, Florida)
- Total: 43.5
- Spread: Buccaneers (-5.5)
- Moneyline: Buccaneers (-278), Falcons (+225)
Dunkel Index predictions:
- Over/Under: Over (43.5)
- ATS: Buccaneers (-5.5)
- Score Prediction: Buccaneers 28, Falcons 18
Baltimore Ravens (7-7) at Cincinnati Bengals (4-10)
- Game Time: 1 p.m. ET | Sunday, December 14, 2025
- Venue: Paycor Stadium (Cincinnati, Ohio)
- Total: 51.5
- Spread: Ravens (-1.5)
- Moneyline: Ravens (-162), Bengals (+136)
Dunkel Index predictions:
- Over/Under: Over (51.5)
- ATS: Bengals (+1.5)
- Score Prediction: Ravens 27, Bengals 25
Arizona Cardinals (3-11) at Houston Texans (9-5)
- Game Time: 1 p.m. ET | Sunday, December 14, 2025
- Venue: NRG Stadium (Houston, Texas)
- Total: 42.5
- Spread: Texans (-10.5)
- Moneyline: Texans (-625), Cardinals (+455)
Dunkel Index predictions:
- Over/Under: Over (42.5)
- ATS: Texans (-10.5)
- Score Prediction: Texans 31, Cardinals 12
Las Vegas Raiders (2-12) at Philadelphia Eagles (9-5)
- Game Time: 1 p.m. ET | Sunday, December 14, 2025
- Venue: Lincoln Financial Field (Philadelphia, Pennsylvania)
- Total: 37.5
- Spread: Eagles (-12.5)
- Moneyline: Eagles (-1000), Raiders (+650)
Dunkel Index predictions:
- Over/Under: Over (37.5)
- ATS: Eagles (-12.5)
- Score Prediction: Eagles 31, Raiders 11
Washington Commanders (4-10) at New York Giants (2-12)
- Game Time: 1 p.m. ET | Sunday, December 14, 2025
- Venue: MetLife Stadium (East Rutherford, New Jersey)
- Total: 46.5
- Spread: Giants (-3)
- Moneyline: Giants (-155), Commanders (+130)
Dunkel Index predictions:
- Over/Under: Over (46.5)
- ATS: Giants (-3)
- Score Prediction: Giants 28, Commanders 21
Buffalo Bills (10-4) at New England Patriots (11-3)
- Game Time: 1 p.m. ET | Sunday, December 14, 2025
- Venue: Gillette Stadium (Foxborough, Massachusetts)
- Total: 49.5
- Spread: Bills (-2.5)
- Moneyline: Bills (-142), Patriots (+120)
Dunkel Index predictions:
- Over/Under: Under (49.5)
- ATS: Patriots (+2.5)
- Score Prediction: Patriots 26, Bills 23
New York Jets (3-11) at Jacksonville Jaguars (10-4)
- Game Time: 1 p.m. ET | Sunday, December 14, 2025
- Venue: EverBank Stadium (Jacksonville, Florida)
- Total: 40.5
- Spread: Jaguars (-14)
- Moneyline: Jaguars (-1053), Jets (+675)
Dunkel Index predictions:
- Over/Under: Over (40.5)
- ATS: Jaguars (-14)
- Score Prediction: Jaguars 34, Jets 12
Cleveland Browns (3-11) at Chicago Bears (10-4)
- Game Time: 1 p.m. ET | Sunday, December 14, 2025
- Venue: Soldier Field (Chicago, Illinois)
- Total: 38.5
- Spread: Bears (-7.5)
- Moneyline: Bears (-380), Browns (+300)
Dunkel Index predictions:
- Over/Under: Over (38.5)
- ATS: Bears (-7.5)
- Score Prediction: Bears 30, Browns 16
Los Angeles Chargers (10-4) at Kansas City Chiefs (6-8)
- Game Time: 1 p.m. ET | Sunday, December 14, 2025
- Venue: GEHA Field at Arrowhead Stadium (Kansas City, Missouri)
- Total: 41.5
- Spread: Chiefs (-4.5)
- Moneyline: Chiefs (-265), Chargers (+215)
Dunkel Index predictions:
- Over/Under: Over (41.5)
- ATS: Chiefs (-4.5)
- Score Prediction: Chiefs 24, Chargers 19
Green Bay Packers (9-4-1) at Denver Broncos (12-2)
- Game Time: 4:25 p.m. ET | Sunday, December 14, 2025
- Venue: Empower Field at Mile High (Denver, Colorado)
- Total: 42.5
- Spread: Packers (-1.5)
- Moneyline: Packers (-122), Broncos (+102)
Dunkel Index predictions:
- Over/Under: Over (42.5)
- ATS: Broncos (+1.5)
- Score Prediction: Broncos 24, Packers 19
Indianapolis Colts (8-6) at Seattle Seahawks (11-3)
- Game Time: 4:25 p.m. ET | Sunday, December 14, 2025
- Venue: Lumen Field (Seattle, Washington)
- Total: 42.5
- Spread: Seahawks (-13.5)
- Moneyline: Seahawks (-1000), Colts (+650)
Dunkel Index predictions:
- Over/Under: Over (42.5)
- ATS: Colts (+13.5)
- Score Prediction: Seahawks 30, Colts 19
Tennessee Titans (2-12) at San Francisco 49ers (10-4)
- Game Time: 4:25 p.m. ET | Sunday, December 14, 2025
- Venue: Levi's Stadium (Santa Clara, California)
- Total: 44.5
- Spread: 49ers (-12.5)
- Moneyline: 49ers (-952), Titans (+625)
Dunkel Index predictions:
- Over/Under: Under (44.5)
- ATS: 49ers (-12.5)
- Score Prediction: 49ers 32, Titans 12
Carolina Panthers (7-7) at New Orleans Saints (4-10)
- Game Time: 4:25 p.m. ET | Sunday, December 14, 2025
- Venue: Caesars Superdome (New Orleans, Louisiana)
- Total: 41.5
- Spread: Panthers (-2.5)
- Moneyline: Panthers (-148), Saints (+124)
Dunkel Index predictions:
- Over/Under: Under (41.5)
- ATS: Saints (+2.5)
- Score Prediction: Panthers 22, Saints 19
Detroit Lions (8-6) at Los Angeles Rams (11-3)
- Game Time: 4:25 p.m. ET | Sunday, December 14, 2025
- Venue: SoFi Stadium (Inglewood, California)
- Total: 55.5
- Spread: Rams (-5.5)
- Moneyline: Rams (-238), Lions (+195)
Dunkel Index predictions:
- Over/Under: Under (55.5)
- ATS: Rams (-5.5)
- Score Prediction: Rams 34, Lions 17
Minnesota Vikings (6-8) at Dallas Cowboys (6-7-1)
- Game Time: 8:20 p.m. ET | Sunday, December 14, 2025
- Venue: AT&T Stadium (Arlington, Texas)
- Total: 48.5
- Spread: Cowboys (-5.5)
- Moneyline: Cowboys (-265), Vikings (+215)
Dunkel Index predictions:
- Over/Under: Over (48.5)
- ATS: Vikings (+5.5)
- Score Prediction: Cowboys 27, Vikings 23
Miami Dolphins (6-7) at Pittsburgh Steelers (7-6)
- Game Time: 8:15 p.m. ET | Monday, December 15, 2025
- Venue: Acrisure Stadium (Pittsburgh, Pennsylvania)
- Total: 42.5
- Spread: Steelers (-3)
- Moneyline: Steelers (-175), Dolphins (+145)
Dunkel Index predictions:
- Over/Under: Over (42.5)
- ATS: Steelers (-3)
- Score Prediction: Steelers 26, Dolphins 20
