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NFL Predictions & Betting Odds - Week 13

25 November 2025 By Data Skrive

The Week 13 NFL slate has plenty of exciting matchups on the docket. Among those contests is the Houston Texans playing the Indianapolis Colts.

We've got you sorted out with a fast summary on every NFL game this week with over/unders, spreads, moneylines, and Dunkel Index predictions. Continue reading for the details.

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Week 13 Games, Betting Info, and Predictions

There are 16 games on the NFL slate this week. Below is a glance at each one:

Green Bay Packers (8-3-1) at Detroit Lions (7-5)

  • Game Time: 1 p.m. ET | Thursday, November 27, 2025
  • Venue: Ford Field (Detroit, Michigan)
  • Total: 48.5
  • Spread: Lions (-2.5)
  • Moneyline: Lions (-155), Packers (+130)

Dunkel Index predictions:

  • Over/Under: Under (48.5)
  • ATS: Lions (-2.5)
  • Score Prediction: Lions 26, Packers 21

Kansas City Chiefs (6-6) at Dallas Cowboys (6-5-1)

  • Game Time: 4:30 p.m. ET | Thursday, November 27, 2025
  • Venue: AT&T Stadium (Arlington, Texas)
  • Total: 53.5
  • Spread: Chiefs (-3.5)
  • Moneyline: Chiefs (-185), Cowboys (+154)

Dunkel Index predictions:

  • Over/Under: Under (53.5)
  • ATS: Chiefs (-3.5)
  • Score Prediction: Chiefs 27, Cowboys 23

Cincinnati Bengals (4-8) at Baltimore Ravens (6-6)

  • Game Time: 8:20 p.m. ET | Thursday, November 27, 2025
  • Venue: M&T Bank Stadium (Baltimore, Maryland)
  • Total: 52.5
  • Spread: Ravens (-7.5)
  • Moneyline: Ravens (-375), Bengals (+295)

Dunkel Index predictions:

  • Over/Under: Under (52.5)
  • ATS: Ravens (-7.5)
  • Score Prediction: Ravens 33, Bengals 19

Chicago Bears (9-3) at Philadelphia Eagles (8-4)

  • Game Time: 3 p.m. ET | Friday, November 28, 2025
  • Venue: Lincoln Financial Field (Philadelphia, Pennsylvania)
  • Total: 43.5
  • Spread: Eagles (-7)
  • Moneyline: Eagles (-340), Bears (+270)

Dunkel Index predictions:

  • Over/Under: Over (43.5)
  • ATS: Eagles (-7)
  • Score Prediction: Eagles 29, Bears 19

New Orleans Saints (2-10) at Miami Dolphins (5-7)

  • Game Time: 1 p.m. ET | Sunday, November 30, 2025
  • Venue: Hard Rock Stadium (Miami Gardens, Florida)
  • Total: 42.5
  • Spread: Dolphins (-5.5)
  • Moneyline: Dolphins (-250), Saints (+205)

Dunkel Index predictions:

  • Over/Under: Over (42.5)
  • ATS: Saints (+5.5)
  • Score Prediction: Dolphins 23, Saints 19

Houston Texans (7-5) at Indianapolis Colts (8-4)

  • Game Time: 1 p.m. ET | Sunday, November 30, 2025
  • Venue: Lucas Oil Stadium (Indianapolis, Indiana)
  • Total: 44.5
  • Spread: Colts (-3)
  • Moneyline: Colts (-170), Texans (+142)

Dunkel Index predictions:

  • Over/Under: Over (44.5)
  • ATS: Colts (-3)
  • Score Prediction: Colts 25, Texans 21

Atlanta Falcons (4-8) at New York Jets (3-9)

  • Game Time: 1 p.m. ET | Sunday, November 30, 2025
  • Venue: MetLife Stadium (East Rutherford, New Jersey)
  • Total: 38.5
  • Spread: Falcons (-3)
  • Moneyline: Falcons (-166), Jets (+140)

Dunkel Index predictions:

  • Over/Under: Over (38.5)
  • ATS: Falcons (-3)
  • Score Prediction: Falcons 24, Jets 21

Arizona Cardinals (3-9) at Tampa Bay Buccaneers (7-5)

  • Game Time: 1 p.m. ET | Sunday, November 30, 2025
  • Venue: Raymond James Stadium (Tampa, Florida)
  • Total: 44.5
  • Spread: Buccaneers (-3.5)
  • Moneyline: Buccaneers (-205), Cardinals (+170)

Dunkel Index predictions:

  • Over/Under: Over (44.5)
  • ATS: Buccaneers (-3.5)
  • Score Prediction: Buccaneers 29, Cardinals 19

San Francisco 49ers (9-4) at Cleveland Browns (3-9)

  • Game Time: 1 p.m. ET | Sunday, November 30, 2025
  • Venue: Huntington Bank Field (Cleveland, Ohio)
  • Total: 35.5
  • Spread: 49ers (-5.5)
  • Moneyline: 49ers (-250), Browns (+205)

Dunkel Index predictions:

  • Over/Under: Over (35.5)
  • ATS: 49ers (-5.5)
  • Score Prediction: 49ers 27, Browns 15

Los Angeles Rams (9-3) at Carolina Panthers (7-6)

  • Game Time: 1 p.m. ET | Sunday, November 30, 2025
  • Venue: Bank of America Stadium (Charlotte, North Carolina)
  • Total: 45.5
  • Spread: Rams (-10)
  • Moneyline: Rams (-575), Panthers (+425)

Dunkel Index predictions:

  • Over/Under: Under (45.5)
  • ATS: Rams (-10)
  • Score Prediction: Rams 30, Panthers 12

Jacksonville Jaguars (8-4) at Tennessee Titans (1-11)

  • Game Time: 1 p.m. ET | Sunday, November 30, 2025
  • Venue: Nissan Stadium (Nashville, Tennessee)
  • Total: 42.5
  • Spread: Jaguars (-5.5)
  • Moneyline: Jaguars (-270), Titans (+220)

Dunkel Index predictions:

  • Over/Under: Over (42.5)
  • ATS: Jaguars (-5.5)
  • Score Prediction: Jaguars 27, Titans 17

Minnesota Vikings (4-8) at Seattle Seahawks (9-3)

  • Game Time: 4:05 p.m. ET | Sunday, November 30, 2025
  • Venue: Lumen Field (Seattle, Washington)
  • Total: 42.5
  • Spread: Seahawks (-12.5)
  • Moneyline: Seahawks (-901), Vikings (+600)

Dunkel Index predictions:

  • Over/Under: Over (42.5)
  • ATS: Seahawks (-12.5)
  • Score Prediction: Seahawks 33, Vikings 14

Buffalo Bills (8-4) at Pittsburgh Steelers (6-6)

  • Game Time: 4:25 p.m. ET | Sunday, November 30, 2025
  • Venue: Acrisure Stadium (Pittsburgh, Pennsylvania)
  • Total: 44.5
  • Spread: Bills (-3)
  • Moneyline: Bills (-166), Steelers (+140)

Dunkel Index predictions:

  • Over/Under: Over (44.5)
  • ATS: Steelers (+3)
  • Score Prediction: Bills 26, Steelers 25

Las Vegas Raiders (2-10) at Los Angeles Chargers (8-4)

  • Game Time: 4:25 p.m. ET | Sunday, November 30, 2025
  • Venue: SoFi Stadium (Inglewood, California)
  • Total: 40.5
  • Spread: Chargers (-9.5)
  • Moneyline: Chargers (-599), Raiders (+440)

Dunkel Index predictions:

  • Over/Under: Over (40.5)
  • ATS: Chargers (-9.5)
  • Score Prediction: Chargers 28, Raiders 14

Denver Broncos (10-2) at Washington Commanders (3-9)

  • Game Time: 8:20 p.m. ET | Sunday, November 30, 2025
  • Venue: Northwest Stadium (Landover, Maryland)
  • Total: 43.5
  • Spread: Broncos (-6.5)
  • Moneyline: Broncos (-310), Commanders (+250)

Dunkel Index predictions:

  • Over/Under: Over (43.5)
  • ATS: Broncos (-6.5)
  • Score Prediction: Broncos 28, Commanders 17

New York Giants (2-10) at New England Patriots (10-2)

  • Game Time: 8:15 p.m. ET | Monday, December 1, 2025
  • Venue: Gillette Stadium (Foxborough, Massachusetts)
  • Total: 46.5
  • Spread: Patriots (-7.5)
  • Moneyline: Patriots (-375), Giants (+295)

Dunkel Index predictions:

  • Over/Under: Over (46.5)
  • ATS: Patriots (-7.5)
  • Score Prediction: Patriots 30, Giants 18

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