Virginia vs. American Dunkel Predictions & Vegas Odds - Dec. 22

The No. 23 Virginia Cavaliers (10-1) take on the American Eagles (7-5) as 28.5-point favorites on Monday, December 22, 2025 at 6 p.m. ET on ACC Network. The matchup's over/under is 156.5.

Virginia heads into this game after an 80-72 victory against Maryland on Saturday. In Virginia's win, Dallin Hall led the way with a team-high 20 points (adding three rebounds and six assists). American enters this contest following a 105-83 loss to VCU on Thursday. Wyatt Nausadis recorded 17 points, one rebound and zero assists for American.

Virginia vs. American Odds and Game Time

• When: Monday, December 22, 2025 at 6 p.m. ET
• Where: John Paul Jones Arena in Charlottesville, Virginia
• Spread favorite: Virginia -28.5
• Moneyline favorite: Virginia -6667
• Moneyline underdog: American +2000
• Over/Under: 156.5 points

How to watch Virginia vs. American

• TV Channel: ACC Network
• Live Stream: Fubo
• Check out the rest of our Dunkel Index NCAA Basketball Picks!

Betting the Over/Under: Virginia vs. American

• Virginia and its opponents have combined to exceed Monday's over/under of 156.5 points five times this season.
• There have been five American games that ended with a combined score over 156.5 points this season.
• The point total for the game of 156.5 is 11.8 points fewer than the combined points per game averages for the Cavaliers (86.5 points per game) and the Eagles (81.8 points per game).
• These two teams surrender a combined 141.2 points per game, 15.3 points less than this contest's over/under.
• On average, the over/under in Virginia's games is 2.1 fewer points than the over/under of 156.5 in this matchup.
• American's games have an average over/under of 155.1 points this season, 1.4 points lower than the over/under for this game.

Betting the Spread: Virginia vs. American

• Virginia has six wins against the spread in 11 games this season.
• This season, the Cavaliers are winless ATS when entering a game as a favorite of 28.5 points or more.
• In American's 10 games this year, it has six wins against the spread.
• Virginia is 3-4 against the spread, and 7-0 overall, at home this season.
• At home, as a 28.5-point favorite or more, Virginia is winless ATS (0-2).
• American is 0-4 overall, with two wins against the spread, away from home.

Betting the Moneyline: Virginia vs. American

• This season, Virginia has been moneyline favorites eight times and won seven of those games.
• The Cavaliers are undefeated in three games this season when favored by -6667 or more on the moneyline.
• Oddsmakers have implied with the moneyline set for this matchup that Virginia has a 98.5% chance to win.
• American has been named as the moneyline underdog five times this season but has yet to come away with a victory in any of those games.
• Oddsmakers have given the Eagles the worst odds of winning they have seen this season with a +2000 moneyline listed for this contest.
• The moneyline set for this matchup implies American has a 4.8% chance of walking away with the win.

Dunkel Index Prediction for Virginia vs. American

• Pick ATS: Virginia (- 28.5)
• Pick OU: Over (156.5)
  
• Prediction: Virginia 94 - American 65