Vanderbilt vs. Wake Forest Dunkel Predictions & Vegas Odds - Dec. 21

The No. 13 Vanderbilt Commodores (11-0) visit the Wake Forest Demon Deacons (9-3) at Lawrence Joel Veterans Memorial Coliseum, starting at 1 p.m. ET on Sunday, December 21, 2025. The Commodores are 4.5-point favorites in the game. The matchup has an over/under of 158.5 points.

Their last time out, Vanderbilt won on Wednesday 77-70 against Memphis in overtime. In the victory, Duke Miles paced Vanderbilt with 22 points. Wake Forest is coming off of a 71-68 win over Longwood in its last outing on Wednesday. In Wake Forest's win, Juke Harris led the team with 19 points (adding eight rebounds and two assists).

Vanderbilt vs. Wake Forest Odds and Game Time

• When: Sunday, December 21, 2025 at 1 p.m. ET
• Where: Lawrence Joel Veterans Memorial Coliseum in Winston-Salem, North Carolina
• Spread favorite: Vanderbilt -4.5
• Moneyline favorite: Vanderbilt -214
• Moneyline underdog: Wake Forest +176
• Over/Under: 158.5 points

How to watch Vanderbilt vs. Wake Forest

• TV Channel: CW (WGN - Chicago)
• Live Stream: Fubo
• Check out the rest of our Dunkel Index NCAA Basketball Picks!

Betting the Over/Under: Vanderbilt vs. Wake Forest

• This season, Vanderbilt and its opponents have combined to outscore Sunday's over/under of 158.5 points seven times.
• In Wake Forest's 12 games this season, six finished with more combined points than Sunday's over/under of 158.5.
• Together, the two teams combine for 179 points per game, 20.5 points more than the total of 158.5 for this matchup.
• This game's point total is 13.6 fewer points than the 144.9 these two teams combine to allow per game in 2024.
• Vanderbilt has a 166.4 average over/under in its games this season, 7.9 more points than the over/under in this contest.
• The over/under for this game is 0.8 points higher than the average over/under in Wake Forest's games this season of 157.7.

Betting the Spread: Vanderbilt vs. Wake Forest

• Vanderbilt is 6-5-0 against the spread this year.
• So far this season, the Commodores have been installed as favorites by a 4.5-point margin or more 11 times and are 6-5 ATS in those games.
• Wake Forest has six wins against the spread in 12 games this season.
• The Demon Deacons have been underdogs by 4.5 points or more two times this year and have covered the spread every time.
• Wake Forest is 3-5 against the spread, and 7-1 overall, at home.
• At home, as a 4.5-point underdog or more, Wake Forest is 3-5 ATS.
• On the road, Vanderbilt has one win ATS (1-1) as 4.5-point favorites or more.

Betting the Moneyline: Vanderbilt vs. Wake Forest

• Vanderbilt has been the moneyline favorite in 10 games this season and picked up the win in all of them.
• The Commodores are undefeated in nine games this season when favored by -214 or more on the moneyline.
• The bookmakers' moneyline implies a 68.2% chance of a victory for Vanderbilt.
• Wake Forest has been chosen as moneyline underdogs in three games this year and has walked away with the win one time (33.3%) in those games.
• The Demon Deacons have been listed as an underdog of +176 or more on two occasions this season and lost both games.
• The moneyline set for this matchup implies Wake Forest has a 36.2% chance of walking away with the win.