USC vs. Seton Hall Dunkel Predictions & Vegas Odds - Nov. 25

The USC Trojans (5-0) host the Seton Hall Pirates (6-0) at Lahaina Civic Center, starting at 5 p.m. ET on Tuesday, November 25, 2025. The Trojans are 7.5-point favorites in the game. The matchup's point total is 146.5.

USC won its last game 70-67 against Boise State on Monday. Rodney Rice's team-leading 27 points led USC in the win. Seton Hall's most recent outing on Monday ended in an 85-74 win against NC State. A.J. Staton-McCray scored 22 points in Seton Hall's victory, leading the team.

USC vs. Seton Hall Odds and Game Time

• When: Tuesday, November 25, 2025 at 5 p.m. ET
• Where: Lahaina Civic Center in Lahaina, Hawaii
• Spread favorite: USC -7.5
• Moneyline favorite: USC -375
• Moneyline underdog: Seton Hall +290
• Over/Under: 146.5 points

How to watch USC vs. Seton Hall

• TV Channel: ESPN
• Check out the rest of our Dunkel Index NCAA Basketball Picks!

Betting the Over/Under: USC vs. Seton Hall

• This season, USC and its opponents have combined to outscore Tuesday's over/under of 146.5 points four times.
• This season, Seton Hall has played just one game with a combined score higher than 146.5 points.
• The total for the matchup of 146.5 is 22.9 points fewer than the combined points per game averages for the Trojans (94.4) and Pirates (75.0).
• These two teams give up a combined 135.2 points per game, 11.3 points less than this contest's over/under.
• USC has seen a 171.8 average over/under in its games this season, 25.3 points more than the over/under in this contest.
• The over/under for this matchup is 13.7 points more than the average over/under in Seton Hall's games this season (132.8 points).

Betting the Spread: USC vs. Seton Hall

• In USC's five games this season, it has three wins against the spread.
• The Trojans have been favored by 7.5 points or more four times this season and are 3-1 ATS in those matchups.
• In Seton Hall's six games this season, it has three wins against the spread.
• The Pirates have been underdogs by 7.5 points or more once this season and covered the spread.
• At home this season, USC has two wins against the spread and is 3-0 overall.
• USC has two wins ATS (2-1) as a 7.5-point favorite or more at home.

Betting the Moneyline: USC vs. Seton Hall

• This season, USC has been listed as the moneyline favorite in five games and won them all.
• The Trojans have entered four games this season favored by -375 or more, and won each of those games.
• The oddsmakers' moneyline implies a 78.9% chance of a victory for USC.
• Seton Hall came away victorious in the one game it played as the moneyline underdog this season.
• The Pirates have played as an underdog of +290 or more just one time this year and came away with a win in that game.
• Seton Hall has an implied victory probability of 25.6% according to the moneyline set by sportsbooks for this matchup.