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Blue Jays vs. Astros Dunkel MLB Picks, Predictions and Prop Bets - June 22

22 June 2026 By Data Skrive

The Toronto Blue Jays and Houston Astros square off in the first of a three-game series on Monday at Rogers Centre, at 7:07 p.m. ET. Dylan Cease (4-3, 2.71 ERA) gets the start for the Blue Jays, who are 38-39 this season and third in the AL East. Hunter Brown (1-0, 1.10 ERA) is the expected starter for the Astros, who are 37-42 and fourth in the AL West.

The Blue Jays are moderate favorites on the moneyline (-126) at home over the Astros (+105). The contest has a total set at 7.5.

Blue Jays vs. Astros Odds, Game Time

  • Game day: Monday, June 22, 2026
  • Game time: 7:07 p.m. ET
  • Location: Toronto, Ontario
  • Stadium: Rogers Centre
  • Favorite: Blue Jays (-126)
  • Underdog: Astros (+105)
  • Over/under: 7.5

How to Watch Blue Jays vs. Astros

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Blue Jays vs. Astros: Betting the Moneyline

  • The Blue Jays have been favored on the moneyline 40 total times this season. They've gone 23-17 in those games.
  • Houston has come away with 25 wins in the 51 contests it has been listed as the underdogs in this season.
  • Toronto has entered 26 games this season favored by -126 or more and is 14-12 in those contests.
  • The Astros have a win-loss record of 20-18 when favored by +105 or worse by sportsbooks this year.
  • Based on this game's moneyline, the Blue Jays' implied win probability is 55.8%.
  • The moneyline set for this matchup implies the Astros have a 48.8% chance of walking away with the win.

Blue Jays vs. Astros: Betting the Spread & Total

  • The Blue Jays have combined with opponents to hit the over on the total 38 times this season for a 38-36-3 record against the over/under.
  • Houston's games have gone over the total in 42 of its 79 chances.
  • The Blue Jays are 39-38-0 against the spread this season.
  • In 79 games with a line this season, the Astros have a mark of 37-42-0 against the spread.
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