Syracuse vs. Mercyhurst Dunkel Predictions & Vegas Odds - Dec. 17

The Syracuse Orange (6-4) host the Mercyhurst Lakers (4-7) at JMA Wireless Dome, beginning at 7 p.m. ET on Wednesday, December 17, 2025. The Orange are 21.5-point favorites in the game. The matchup has an over/under of 135.5 points.

In its last time out, Syracuse lost 70-69 to Hofstra on Saturday. In the losing effort, JJ Starling paced Syracuse with 15 points. Mercyhurst enters this contest on the heels of an 80-47 loss to Davidson on Saturday. Bernie Blunt scored 15 points in Mercyhurst's loss, leading the team.

Syracuse vs. Mercyhurst Odds and Game Time

• When: Wednesday, December 17, 2025 at 7 p.m. ET
• Where: JMA Wireless Dome in Syracuse, New York
• Spread favorite: Syracuse -21.5
• Over/Under: 135.5 points

How to watch Syracuse vs. Mercyhurst

• TV Channel: ACC Network Extra
• Check out the rest of our Dunkel Index NCAA Basketball Picks!

Betting the Over/Under: Syracuse vs. Mercyhurst

• Syracuse and its opponents have hit the over on this game's total (135.5 points) four times this season.
• There have been four Mercyhurst games that ended with a combined score over 135.5 points this season.
• The total for the matchup of 135.5 is 2.6 points fewer than the combined points per game averages for the Orange (72.6) and Lakers (65.5).
• These two teams give up a combined 131.6 points per game, 3.9 points less than this contest's over/under.
• On average, Syracuse has had a 137.6-point over/under in its games this season, 2.1 more points than the over/under in this contest.
• Mercyhurst's games have an average over/under of 132.2 points this season, 3.3 fewer points than the over/under for this contest.

Betting the Spread: Syracuse vs. Mercyhurst

• Syracuse is 5-5-0 against the spread this year.
• This season, the Orange have two ATS wins in three games as a favorite of 21.5 points or more.
• In Mercyhurst's nine games this season, it has five wins against the spread.
• The Lakers have been underdogs by 21.5 points or more three times this year and have covered the spread twice.
• Syracuse is 5-1 overall, and 3-3 against the spread, at home.
• At home, Syracuse has two wins ATS (2-1) as a 21.5-point favorite or more.
• On the road, Mercyhurst is 4-4 against the spread, and 1-7 overall.