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Cardinals vs. Nationals Dunkel MLB Picks, Predictions and Prop Bets - Sept. 18

18 September 2026 By Data Skrive

The St. Louis Cardinals and Washington Nationals clash on Friday at 8:15 p.m. ET, beginning a three-game series at Busch Stadium. Kyle Leahy (10-4, 3.33 ERA) will start for the Cardinals, who are 75-78 this season and fourth in the NL Central. Cade Cavalli (12-5, 3.12 ERA) is expected to start for the Nationals, who are 71-82 and fourth in the NL East.

With moneyline odds of -110 for the Cardinals and -110 for the Nationals, this could be a close contest. The total in this contest is set at 7.5.

Cardinals vs. Nationals Odds, Game Time

  • Game day: Friday, September 18, 2026
  • Game time: 8:15 p.m. ET
  • Location: St. Louis, Missouri
  • Stadium: Busch Stadium
  • Favorite: Cardinals (-110)
  • Underdog: Nationals (-110)
  • Over/under: 7.5

How to Watch Cardinals vs. Nationals

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Cardinals vs. Nationals: Betting the Moneyline

  • The Cardinals have won 51% of the games this season when they were favored on the moneyline (26-25).
  • Washington has been pegged as an underdog in 117 games this year and has walked away with the win 49 times (41.9%) in those games.
  • St. Louis is 26-27 this season when entering a game favored by -110 or more on the moneyline.
  • The Nationals have a win-loss record of 49-68 when favored by -110 or worse by bookmakers this year.
  • The Cardinals have an implied moneyline win probability of 52.4% in this game.
  • The moneyline set for this matchup implies the Nationals have a 52.4% chance of walking away with the win.

Cardinals vs. Nationals: Betting the Spread & Total

  • The Cardinals have had an over/under set by oddsmakers 153 times, and have combined with opponents to go over the total in 68 of those games (68-75-10).
  • Washington and its opponents have gone over the total this season in 80 of its 153 opportunities.
  • The Cardinals have an 84-69-0 record against the spread this season (covering 54.9% of the time).
  • The Nationals are 85-68-0 against the spread in their 153 games that had a posted line this season.
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