Southern Miss vs. North Florida Dunkel Predictions & Vegas Odds - Nov. 22

The Southern Miss Golden Eagles (2-3) visit the North Florida Ospreys (1-3) at Pensacola Bay Center, beginning at 8 p.m. ET on Saturday, November 22, 2025. The Ospreys are 9.5-point underdogs in the game. The matchup has an over/under of 154.5 points.

Southern Miss heads into this matchup on the heels of an 82-59 win over William Carey on Tuesday. In Southern Miss' win, Isaac Tavares led the way with a team-high 13 points (adding eight rebounds and four assists). North Florida dropped its most recent outing 86-78 against Wofford on Wednesday. North Florida got a team-leading 22 points from Kamrin Oriol in the loss.

Southern Miss vs. North Florida Odds and Game Time

• When: Saturday, November 22, 2025 at 8 p.m. ET
• Where: Pensacola Bay Center in Pensacola, Florida
• Spread favorite: Southern Miss -9.5
• Moneyline favorite: Southern Miss -546
• Moneyline underdog: North Florida +407
• Over/Under: 154.5 points

How to watch Southern Miss vs. North Florida

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Betting the Over/Under: Southern Miss vs. North Florida

• Southern Miss and its opponent combined to score over 154.5 points, the current matchup's point total, in 10 of 31 games last season.
• A total of 22 North Florida's games last season (out of 30) had more than 154.5 total points scored.
• These teams averaged a combined 154.1 points per game a season ago, 0.4 fewer points than the total of 154.5 set for this game.
• The Golden Eagles and the Ospreys saw their opponents average a combined 6.3 more points per game last season than the point total of 154.5 set in this game.
• The average over/under Southern Miss had set in games last year was 7.3 fewer points than this outing's point total.
• The average point total for North Florida in 2024 was 13.1 points higher than this game's over/under.

Betting the Spread: Southern Miss vs. North Florida

• Southern Miss put together a 14-17-0 ATS record last year.
• North Florida compiled a 13-17-0 record against the spread last season.
• When playing as at least 9.5-point underdogs last year, the Ospreys had an ATS record of 3-3.
• North Florida was 6-6 overall, and 4-8 against the spread, at home last year.
• North Florida had one win ATS (1-2) as a 9.5-point underdog or more at home last season.
• Away from home last season, Southern Miss was 1-13 overall and 6-8 against the spread.

Betting the Moneyline: Southern Miss vs. North Florida

• Southern Miss has not played a game this season while listed as the moneyline favorite.
• The Golden Eagles have not been a bigger favorite this season than the -546 moneyline set for this game.
• The bookmakers' moneyline implies a 84.5% chance of a victory for Southern Miss.
• North Florida was defeated in both of the games it has played as moneyline underdogs this season.
• The Ospreys have been listed as an underdog of +407 or more on two occasions this season and lost both games.
• Bookmakers have implied with the moneyline set for this matchup that North Florida has a 19.7% chance of pulling out a win.