Seahawks vs. 49ers Week 18 Dunkel NFL Picks, Predictions and Odds

The Seattle Seahawks (13-3) and San Francisco 49ers (12-4) will face off, with both teams on win streaks -- the Seahawks six in a row, the 49ers six in a row. Seattle is a slight favorite (-2.5). An over/under of 47.5 points has been established for the matchup.

The Seahawks rank eighth in total offense (350.8 yards per game) and sixth in total defense (292.9 yards allowed per game) this year. The 49ers are posting 362.6 total yards per game on offense this season (seventh-ranked). Meanwhile, they are surrendering 338.9 total yards per game (19th-ranked).

Seahawks vs. 49ers Odds and Game Time

• Date: Saturday, January 3, 2026
• Time: 8 p.m. ET
• City: Santa Clara, California
• Venue: Levi's Stadium
• Total: 47.5 points
• Spread: Seahawks -2.5
• Moneyline: Seahawks (-148), 49ers (+124)

How to watch Seahawks vs. 49ers

• TV Channel: ESPN2
• Live Stream: Fubo

Betting the Over/Under: Seahawks vs. 49ers

• In seven of 16 games this season, the Seahawks and their opponents have combined to total more than 47.5 points.
• So far this season, nine of Seattle's 16 games have hit the over.
• The 49ers have combined with their opponents to score more than 47.5 points in eight of 16 games this season.
• San Francisco and its opponent have combined to hit the over 10 out of 16 times this season.
• These two teams score a combined 56.5 points per game, nine more points than this matchup's point total.
• Combined, these teams give up 40.5 points per game, seven fewer points than this matchup's total.

Betting the Spread: Seahawks vs. 49ers

• Seattle is 11-5-0 ATS this season.
• When playing as at least 2.5-point favorites this season, the Seahawks have an ATS record of 7-3.
• The 49ers have covered 11 times in 16 chances against the spread this year.
• San Francisco has been an underdog by 2.5 points or more four times this year, and covered the spread in one of those matchups.
• The 49ers are 4-3 against the spread, and 5-2 overall, at home.
• At home, San Francisco is winless ATS (0-1) as 2.5-point underdogs or more.
• The Seahawks are 7-1 overall, and 7-1 against the spread, on the road.
• On the road, as 2.5-point favorites or more, Seattle is 3-1 ATS.

Betting the Moneyline: Seahawks vs. 49ers

• Seattle has a 12-1 record in games they were favored on the moneyline (winning 92.3% of those games).
• The 49ers have been underdogs in four games this season and won one (25%) of those contests.
• In games it has played as a moneyline favorite with odds of -148 or shorter, Seattle has a 9-1 record (winning 90% of its games).
• This season, San Francisco has won one of its four games when it is the underdog by at least +124 on the moneyline.
• Based on this matchup's moneyline, the Seahawks have an implied win probability of 59.7%.

Dunkel Prediction for Seahawks vs. 49ers

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