Padres vs. Cardinals Dunkel MLB Picks, Predictions and Prop Bets - May 7

The San Diego Padres and St. Louis Cardinals square off in the first of a four-game series on Thursday at Petco Park, at 10:10 p.m. ET. Michael King (3-2, 2.95 ERA) will start for the Padres, who are 22-14 this season and second in the NL West. Matthew Liberatore (1-1, 4.50 ERA) is starting for the Cardinals, who are 21-15 and second in the NL Central.

With the Cardinals (+140) visiting, the Padres (-168) are a solid favorite on the moneyline. The contest has an over/under set at 8.

Padres vs. Cardinals Odds, Game Time

• Game day: Thursday, May 7, 2026
• Game time: 10:10 p.m. ET
• Location: San Diego, California
• Stadium: Petco Park
• Favorite: Padres (-168)
• Underdog: Cardinals (+140)
• Over/under: 8

How to Watch Padres vs. Cardinals

• TV Channel: ESPN
• Live Stream: Fubo (Watch for free)

Bet now on FanDuel Sportsbook!

Padres vs. Cardinals: Betting the Moneyline

• The Padres have gone 12-8 in games they were favored on the moneyline (winning 60% of those games).
• St. Louis has been underdogs in 32 games this season and has come away with the win 19 times (59.4%) in those contests.
• San Diego has a record of 4-1 when favored by -168 or more by bookmakers this season.
• This season, the Cardinals have been victorious two times in four chances when named as an underdog of at least +140 or worse on the moneyline.
• Based on this matchup's moneyline, the Padres' implied win probability is 62.7%.
• The Cardinals have an implied victory probability of 41.7% according to the moneyline set by oddsmakers for this matchup.

Padres vs. Cardinals: Betting the Spread & Total

• The Padres have had an over/under set by bookmakers 36 times, and have combined with opponents to go over the total in 16 of those games (16-18-2).
• Games involving St. Louis have gone over the total set by bookmakers in 17 of 36 chances this season.
• The Padres have collected a 21-15-0 record ATS this season (covering 58.3% of the time).
• The Cardinals are 22-14-0 against the spread in their 36 games that had a posted line this season.