Padres vs. Cardinals Dunkel MLB Picks, Predictions and Prop Bets - May 7

The San Diego Padres and St. Louis Cardinals square off in the first of a four-game series on Thursday at Petco Park, at 10:10 p.m. ET. Michael King (3-2, 2.95 ERA) will start for the Padres, who are 22-14 this season and second in the NL West. Matthew Liberatore (1-1, 4.50 ERA) is starting for the Cardinals, who are 21-15 and second in the NL Central.

At home, the Padres are favored to win on the moneyline (-168) over the Cardinals (+140). The over/under for the Padres-Cardinals game is 8.

Padres vs. Cardinals Odds, Game Time

• Game day: Thursday, May 7, 2026
• Game time: 10:10 p.m. ET
• Location: San Diego, California
• Stadium: Petco Park
• Favorite: Padres (-168)
• Underdog: Cardinals (+140)
• Over/under: 8

How to Watch Padres vs. Cardinals

• TV Channel: ESPN
• Live Stream: Fubo (Watch for free)

Bet now on FanDuel Sportsbook!

Padres vs. Cardinals: Betting the Moneyline

• The Padres have won 12 of the 20 games they were favored on the moneyline this season (60%).
• St. Louis has come away with 19 wins in the 32 contests it has been listed as the underdogs in this season.
• San Diego has entered five games this season favored by -168 or more and is 4-1 in those contests.
• The Cardinals have a win-loss record of 2-2 when favored by +140 or worse by oddsmakers this year.
• The Padres have a 62.7% chance to win this game based on the moneyline's implied probability.
• The moneyline set for this matchup implies the Cardinals have a 41.7% chance of coming away with a victory in the contest.

Padres vs. Cardinals: Betting the Spread & Total

• In the 36 games in which oddsmakers have set an over/under for the Padres, they have combined with opponents to go over the total 16 times (16-18-2).
• St. Louis and its opponents have hit the over in 17 of its 36 games with a total this season.
• The Padres have a 21-15-0 record ATS this season (covering 58.3% of the time).
• The Cardinals are 22-14-0 against the spread in their 36 games that had a posted line this season.