Purdue vs. Eastern Illinois Dunkel Predictions & Vegas Odds - Nov. 28

The No. 1 Purdue Boilermakers (6-0) host the Eastern Illinois Panthers (2-4) at Mackey Arena, tipping off at 12 p.m. ET on Friday, November 28, 2025. The Boilermakers are 40.5-point favorites in the game. The matchup's point total is set at 141.5.

Purdue is coming off of an 86-56 win over Texas Tech in its most recent outing on Friday. Oscar Cluff's team-leading 15 points led Purdue in the victory. Eastern Illinois heads into this contest following an 81-60 loss to Central Arkansas on Tuesday. Zion Fruster scored 21 points in Eastern Illinois' loss, leading the team.

Purdue vs. Eastern Illinois Odds and Game Time

• When: Friday, November 28, 2025 at 12 p.m. ET
• Where: Mackey Arena in West Lafayette, Indiana
• Spread favorite: Purdue -40.5
• Over/Under: 141.5 points

How to watch Purdue vs. Eastern Illinois

• TV Channel: Big Ten Network
• Live Stream: Fubo
• Check out the rest of our Dunkel Index NCAA Basketball Picks!

Betting the Over/Under: Purdue vs. Eastern Illinois

• Purdue and its opponents have hit the over on this game's total (141.5 points) five times this season.
• This season, Eastern Illinois has played only one game with a combined score over 141.5 points.
• The point total for the matchup of 141.5 is 5.2 points fewer than the combined points per game averages for the Boilermakers (86.5) and Panthers (60.2).
• The 140.8 points per game these two teams surrender to opponents combined this season are 0.7 less than the 141.5-point total in this contest.
• This season, the average over/under for Purdue's games is 155.5 points, 14.0 more than the total of 141.5 points set for this contest.
• Eastern Illinois' games have an average over/under of 132 points this season, 9.5 fewer points than the over/under for this matchup.

Betting the Spread: Purdue vs. Eastern Illinois

• Purdue has two wins against the spread in six games this year.
• Against the spread, Eastern Illinois is 3-2-0 this year.
• Purdue has not covered the spread at home, and is 3-0 overall there, this year.
• Eastern Illinois is 0-4 overall, with two wins against the spread, in away games.