Phillies vs. Brewers Dunkel MLB Picks, Predictions and Prop Bets - Sept. 22

The Philadelphia Phillies host the Milwaukee Brewers to open a three-game series at Citizens Bank Park, with first pitch at 6:40 p.m. ET on Tuesday. Zack Wheeler (13-5, 2.99 ERA) gets the start for the Phillies, who are 86-70 this season and second in the NL East. Dustin May (7-9, 4.61 ERA) is expected to start for the Brewers, who are 98-58 and first in the NL Central.

With the Brewers (+118) visiting, the Phillies (-143) are a solid favorite on the moneyline. The over/under in this contest is 7.5.

Phillies vs. Brewers Odds, Game Time

• Game day: Tuesday, September 22, 2026
• Game time: 6:40 p.m. ET
• Location: Philadelphia, Pennsylvania
• Stadium: Citizens Bank Park
• Favorite: Phillies (-143)
• Underdog: Brewers (+118)
• Over/under: 7.5

How to Watch Phillies vs. Brewers

• TV Channel: NBCS-PH and BREW
• Live Stream: Fubo (Watch for free)

Bet now on FanDuel Sportsbook!

Phillies vs. Brewers: Betting the Moneyline

• The Phillies have won 63.2% of the games this season when they were favored on the moneyline (74-43).
• Milwaukee has won in 18, or 52.9%, of the 34 contests it has been named as odds-on underdogs in this year.
• This season Philadelphia has won 57 of its 76 games, or 75%, when favored by at least -143 on the moneyline.
• This season, the Brewers have come away with a win three times in seven chances when named as an underdog of at least +118 or worse on the moneyline.
• The implied moneyline probablility for this matchup gives the Phillies a 58.8% chance to win.
• The Brewers have an implied victory probability of 45.9% according to the moneyline set for this matchup.

Phillies vs. Brewers: Betting the Spread & Total

• The Phillies have had an over/under set by oddsmakers 156 times, and have combined with opponents to go over the total in 73 of those games (73-75-8).
• Milwaukee and its opponents have hit the over in 69 of its 156 games with a total this season.
• The Phillies have gone 67-89-0 against the spread this season.
• The Brewers have an against the spread mark of 80-76-0 in 156 games with a line this season.