Penn State vs. Boston University Dunkel Predictions & Vegas Odds - Nov. 25

The Penn State Nittany Lions (5-1) host the Boston University Terriers (3-3) at Bryce Jordan Center, tipping off at 7 p.m. ET on Tuesday, November 25, 2025. The Terriers are 14.5-point underdogs in the game. The matchup's point total is set at 144.5.

Penn State fell in its last game 77-65 against Providence on Saturday. In the loss, Freddie Filione V paced Penn State with 22 points. Boston University's most recent outing on Saturday ended in a 75-74 win against Harvard. In Boston University's win, Chance Gladden led the way with 20 points (adding two rebounds and three assists).

Penn State vs. Boston University Odds and Game Time

• When: Tuesday, November 25, 2025 at 7 p.m. ET
• Where: Bryce Jordan Center in University Park, Pennsylvania
• Spread favorite: Penn State -14.5
• Moneyline favorite: Penn State -1449
• Moneyline underdog: Boston University +810
• Over/Under: 144.5 points

How to watch Penn State vs. Boston University

• TV Channel: Peacock
• Check out the rest of our Dunkel Index NCAA Basketball Picks!

Betting the Over/Under: Penn State vs. Boston University

• Penn State and its opponents have combined to go over Tuesday's total of 144.5 points three times this season.
• This season, four games Boston University has played finished with a combined score over 144.5 points.
• The over/under for the contest of 144.5 is 4.9 points fewer than the combined points per game averages for the Nittany Lions (79.2) and Terriers (70.2).
• The 142.5 points per game these two teams surrender to opponents combined this season are 2.0 less than the 144.5-point total in this contest.
• Penn State has seen a 147.2 average over/under in its games this season, 2.7 points more than the over/under in this matchup.
• A difference of 0.2 points separates the average over/under in Boston University's games (144.7 points) and this matchup's over/under (144.5).

Betting the Spread: Penn State vs. Boston University

• Penn State has covered the spread twice this season.
• This season, the Nittany Lions have one against the spread win in two games as a favorite of 14.5 points or more.
• Boston University has three wins against the spread in six games this year.
• The Terriers have been underdogs by 14.5 points or more one time this year and have not covered the spread once.
• At home this season, Penn State is winless against the spread, and 3-0 overall.
• Penn State is winless ATS (0-1) as a 14.5-point favorite or greater at home.
• On the road, Boston University has just one win against the spread and are 1-2 overall.

Betting the Moneyline: Penn State vs. Boston University

• Penn State has been listed as the moneyline favorite five times this season and has won all of those games.
• The Nittany Lions have played as a favorite of -1449 or more twice this season and won both games.
• Bookmakers have implied with the moneyline set for this matchup that Penn State has a 93.5% chance to win.
• Boston University has been a moneyline underdog in four games this season and has come away with the win two times (50%) in those contests.
• The Terriers have played as an underdog of +810 or more just one time this year and came away with a loss in that game.
• Boston University has an implied victory probability of 11% according to the moneyline set for this matchup.