Patrick Mahomes vs. Colts - NFL - Player Props, Lines and Trends
21 November 2025
Before you bet on Patrick Mahomes' player prop betting options in Sunday's game, which starts at 1 p.m. ET on CBS, take a look at some key stats and trends to know. Mahomes and the Kansas City Chiefs (5-5) have a Week 12 matchup with the Indianapolis Colts (8-2) at GEHA Field at Arrowhead Stadium.
Keep reading for more Dunkel stats, insights and trends.Patrick Mahomes Player Props
| Pass Yds Over/Under | Pass Yds Over Payout | Pass TDs Over/Under | Pass TDs Over Payout | Rush Yds Over/Under | Rush Yds Over Payout | Anytime TD Odds |
|---|---|---|---|---|---|---|
| 272.5 | -113 | 1.5 | -179 | 23.5 | -109 | +290 |
Mahomes Passing Insights
- Sunday's prop bet for Mahomes is 272.5 passing yards, 10.0 more than his average of 262.5 on the season.
- In four of 10 games this season, Mahomes has thrown for over 272.5 yards.
- Mahomes' passing yards average (262.5) is higher than his average prop total this season (255.7) by 6.8 yards.
- Mahomes has gone over his passing yards total six times this year (60.0%).
- Mahomes has thrown for a touchdown in nine of 10 games this season, with more than one TD pass four times.
- In five of 10 games this season, Mahomes has thrown an interception, with more than one INT on one occasion.
Mahomes Rushing Insights
- Mahomes rushes for 28.8 yards per game this season, which outpaces Sunday's prop total of 23.5 yards.
- Mahomes has totaled more than 23.5 yards on the ground in six of 10 games so far this season.
- The average rushing yards prop Mahomes has had set this season (24.9) is just a bit lower than his rushing yard average on the year (28.8).
- Mahomes has hit the over on his rushing yards prop bet six times so far this season (in 10 opportunities).
- Mahomes has rushed for a TD in four games this year.
Indianapolis Colts Rankings
- The 235.3 passing yards per game allowed by the Colts defense makes them the NFL's 25th-ranked pass defense.
- The Colts' defense is 15th in the league by conceding 1.6 passing touchdowns per game to opposing offenses (16 total passing TDs).
- The Colts' defense has collected 10 interceptions against opposing QBs (one per game), which ranks fourth in the league.
For more expert NFL prop picks and best bets, visit Dunkel Index Best NFL Player Props today.
Last Five Games
| Opponent | Date | Week | Passing Stats | Rushing Stats |
|---|---|---|---|---|
| vs. Broncos | 11/16/2025 | Week 11 | 29-for-45 / 276 YDS / 1 TD / 1 INT | 1 ATT / 3 YDS / 0 TDs |
| vs. Bills | 11/2/2025 | Week 9 | 15-for-34 / 250 YDS / 0 TDs / 1 INT | 1 ATT / 5 YDS / 0 TDs |
| vs. Commanders | 10/27/2025 | Week 8 | 25-for-34 / 299 YDS / 3 TDs / 2 INTs | 4 ATT / 30 YDS / 0 TDs |
| vs. Raiders | 10/19/2025 | Week 7 | 26-for-35 / 286 YDS / 3 TDs / 0 INTs | 4 ATT / 28 YDS / 0 TDs |
| vs. Lions | 10/12/2025 | Week 6 | 22-for-30 / 257 YDS / 3 TDs / 0 INTs | 10 ATT / 32 YDS / 1 TD |
