Oklahoma State vs. Nicholls State Dunkel Predictions & Vegas Odds - Nov. 22

The Oklahoma State Cowboys (5-0) host the Nicholls State Colonels (0-4) at Gallagher-Iba Arena, starting at 2 p.m. ET on Saturday, November 22, 2025. The Cowboys are 24.5-point favorites in the game. The matchup's over/under is 158.5.

Oklahoma State enters this matchup after a 103-95 victory over South Florida on Wednesday. Vyctorius Miller scored a team-best 24 points for Oklahoma State in the victory. Nicholls State is coming off of a 99-79 loss to Murray State in its last game on Saturday. Jalik Dunkley scored a team-high 18 points for Nicholls State in the loss.

Oklahoma State vs. Nicholls State Odds and Game Time

• When: Saturday, November 22, 2025 at 2 p.m. ET
• Where: Gallagher-Iba Arena in Stillwater, Oklahoma
• Spread favorite: Oklahoma State -24.5
• Moneyline favorite: Oklahoma State -10000
• Moneyline underdog: Nicholls State +2667
• Over/Under: 158.5 points

How to watch Oklahoma State vs. Nicholls State

• TV Channel: ESPN+
• Check out the rest of our Dunkel Index NCAA Basketball Picks!

Betting the Over/Under: Oklahoma State vs. Nicholls State

• Oklahoma State and its opponent combined to score over 158.5 points, the current matchup's point total, in 10 of 32 games last season.
• Nicholls State's games went over 158.5 total points scored in six of 30 matchups last year.
• These two teams averaged a combined 147 points per game a season ago, 11.5 fewer points than the total of 158.5 set for this game.
• Opponents of the two teams averaged a combined 12.6 fewer points per game (145.9) last season than this game's total of 158.5 points.
• Oklahoma State's average point total in outings last year was 149.3, 9.2 points less than the over/under in this game.
• Nicholls State's games in 2024 averaged a total of 143.6 points, 14.9 fewer than the point total in this matchup.

Betting the Spread: Oklahoma State vs. Nicholls State

• Oklahoma State went 14-18-0 ATS last season.
• Nicholls State compiled a 19-11-0 record against the spread last year.
• The Colonels covered the spread once last season (1-1 ATS) when playing as at least 24.5-point underdogs.
• Oklahoma State was 7-8 against the spread, and 12-3 overall, at home last year.
• On the road last season, Nicholls State was 12-4 against the spread and 8-8 overall.

Betting the Moneyline: Oklahoma State vs. Nicholls State

• Oklahoma State won all 12 of the games in which it was the moneyline favorite last season.
• The Cowboys never played a game last season with moneyline odds of -10000 or shorter.
• Based on this contest's moneyline, Oklahoma State's implied win probability is 99.0%.
• Last season, Nicholls State won seven out of the 17 games, or 41.2%, in which it was the underdog.
• The Colonels played as an underdog of +2667 or more twice last season and lost both games.
• The moneyline for this contest implies a 3.6% chance of a victory for Nicholls State.