Yankees vs. Rays Dunkel MLB Picks, Predictions and Prop Bets - Sept. 23

The New York Yankees host the Tampa Bay Rays at 7:05 p.m. ET on Wednesday. Gerrit Cole (9-9, 3.63 ERA) will start for the Yankees, who are 90-67 this season and second in the AL East. Ian Seymour (9-7, 4.38 ERA) is expected to start for the Rays, who are 96-61 and first in the AL East.

The Rays (+114) are on the road versus the favored Yankees (-138). The contest has an over/under set at 6.5.

Yankees vs. Rays Odds, Game Time

• Game day: Wednesday, September 23, 2026
• Game time: 7:05 p.m. ET
• Location: The Bronx, New York
• Stadium: Yankee Stadium
• Favorite: Yankees (-138)
• Underdog: Rays (+114)
• Over/under: 6.5

How to Watch Yankees vs. Rays

• TV Channel: Amazon Prime Video and RAYS
• Live Stream: Fubo (Watch for free)

Bet now on FanDuel Sportsbook!

Yankees vs. Rays: Betting the Moneyline

• The Yankees are 75-52 in games they were favored on the moneyline (winning 59.1% of those games).
• Tampa Bay has been pegged as an underdog in 50 games this year and has walked away with the win 26 times (52%) in those games.
• New York is 47-36 this season when entering a game favored by -138 or more on the moneyline.
• The Rays have a mark of 9-7 in contests where bookmakers favor them by +114 or worse on the moneyline.
• The Yankees have a 58% chance to win this matchup based on the moneyline's implied probability.
• Bookmakers have implied with the moneyline set for this matchup that the Rays have a 46.7% chance of pulling out a win.

Yankees vs. Rays: Betting the Spread & Total

• The Yankees have played in 157 games with set over/under, and have combined with opponents to go over the total 72 times (72-80-5).
• Tampa Bay and its opponents have gone over the total this season in 70 of its 157 opportunities.
• The Yankees are 79-78-0 ATS this season.
• The Rays are 83-74-0 against the spread in their 157 games with a line set by sportsbooks this season.