Yankees vs. Rays Dunkel MLB Picks, Predictions and Prop Bets - Sept. 22

The New York Yankees host the Tampa Bay Rays to start a four-game series at Yankee Stadium, with first pitch at 1:05 p.m. ET on Tuesday. Carlos Rodon (6-3, 2.95 ERA) gets the start for the Yankees, who are 89-66 this season and second in the AL East. Nick Martinez (15-4, 2.94 ERA) is expected to start for the Rays, who are 95-60 and first in the AL East.

The Yankees are moderate favorites on the moneyline (-138) at home over the Rays (+113). The over/under for the Yankees-Rays game is 7.

Yankees vs. Rays Odds, Game Time

• Game day: Tuesday, September 22, 2026
• Game time: 1:05 p.m. ET
• Location: The Bronx, New York
• Stadium: Yankee Stadium
• Favorite: Yankees (-138)
• Underdog: Rays (+113)
• Over/under: 7

How to Watch Yankees vs. Rays

• TV Channel: YES and RAYS
• Live Stream: Fubo (Watch for free)

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Yankees vs. Rays: Betting the Moneyline

• The Yankees have won 74 of the 125 games they were the moneyline favorite this season (59.2%).
• Tampa Bay has won in 25, or 52.1%, of the 48 contests it has been named as odds-on underdogs in this year.
• New York has a record of 46-36 in games when oddsmakers favor them by at least -138 on the moneyline.
• The Rays have a mark of 9-6 in contests where oddsmakers favor them by +113 or worse on the moneyline.
• The Yankees have a 58% chance to win this game based on the moneyline's implied probability.
• The moneyline set for this matchup implies the Rays have a 46.9% chance of walking away with the win.

Yankees vs. Rays: Betting the Spread & Total

• The Yankees have played in 155 games with set over/under, and have combined with opponents to go over the total 71 times (71-79-5).
• Tampa Bay and its opponents have gone over the total this season in 69 of its 155 opportunities.
• The Yankees have gone 78-77-0 against the spread this season.
• The Rays are 82-73-0 against the spread in their 155 games that had a posted line this season.