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Twins vs. White Sox Dunkel MLB Picks, Predictions and Prop Bets - Aug. 22

22 August 2025 By Data Skrive

The Minnesota Twins and Chicago White Sox clash on Friday at 7:40 p.m. ET, beginning a three-game series at Rate Field. Zebby Matthews (3-4, 5.06 ERA) will start for the Twins, who are 58-69 this season and fourth in the AL Central. Aaron Civale (3-8, 4.88 ERA) is expected to start for the White Sox, who are 45-82 and fifth in the AL Central.

The Twins are currently a moderate moneyline favorite (-135) on the road at the White Sox (+114). The game's total is set at 8.5.

Twins vs. White Sox Odds, Game Time

  • Game day: Friday, August 22, 2025
  • Game time: 7:40 p.m. ET
  • Location: Chicago, Illinois
  • Stadium: Rate Field
  • Favorite: Twins (-135)
  • Underdog: White Sox (+114)
  • Over/under: 8.5

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Twins vs. White Sox: Betting the Moneyline

  • The Twins have won 36 of the 73 games they were favored on the moneyline this season (49.3%).
  • Chicago has been underdogs in 125 games this season and has come away with the win 44 times (35.2%) in those contests.
  • Minnesota is 23-16 this season when entering a game favored by -135 or more on the moneyline.
  • This season, the White Sox have come away with a win 41 times in 113 chances when named as an underdog of at least +114 or worse on the moneyline.
  • The Twins have an implied moneyline win probability of 57.4% in this matchup.
  • Sportsbooks have implied with the moneyline set for this matchup that the White Sox have a 46.7% chance of pulling out a win.

Twins vs. White Sox: Betting the Spread & Total

  • The Twins have played in 126 games with an over/under set, and have combined with their opponents to go over the total 54 times (54-65-7).
  • Chicago's games have gone over the total in 55 of its 127 chances.
  • The Twins have collected a 65-61-0 record ATS this season (covering 51.6% of the time).
  • The White Sox are 73-54-0 against the spread in their 127 games with a line set by sportsbooks this season.
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