Loyola Chicago vs. Northern Illinois Dunkel Predictions & Vegas Odds - Nov. 21

The Loyola Chicago Ramblers (1-4) host the Northern Illinois Huskies (2-3) at Joseph J. Gentile Arena, tipping off at 8 p.m. ET on Friday, November 21, 2025. The Ramblers are 13.5-point favorites in the game. The matchup has a point total of 150.5.

In its last time out, Loyola Chicago lost 80-67 to Colorado State on Sunday. In Loyola Chicago's loss, Justin Moore led the way with a team-high 13 points (adding two rebounds and three assists). Northern Illinois heads into this matchup after a 70-57 loss to Northern Iowa on Tuesday. Dylan Ducommun scored a team-leading 12 points for Northern Illinois in the loss.

Loyola Chicago vs. Northern Illinois Odds and Game Time

• When: Friday, November 21, 2025 at 8 p.m. ET
• Where: Joseph J. Gentile Arena in Chicago, Illinois
• Spread favorite: Loyola Chicago -13.5
• Moneyline favorite: Loyola Chicago -1220
• Moneyline underdog: Northern Illinois +744
• Over/Under: 150.5 points

How to watch Loyola Chicago vs. Northern Illinois

• TV Channel: Marquee Sports Network
• Live Stream: Fubo
• Check out the rest of our Dunkel Index NCAA Basketball Picks!

Betting the Over/Under: Loyola Chicago vs. Northern Illinois

• Loyola Chicago and its opponents have combined to score more than 150.5 points in a game twice this season.
• There have been two games featuring Northern Illinois this season with more combined points than Friday's over/under of 150.5.
• Together, the two teams combine for 153.2 points per game, 2.7 points more than the total of 150.5 for this matchup.
• This matchup's point total is 9.3 less than the 159.8 points these two teams combine to give up per game.
• Loyola Chicago has a 151.8 average over/under in its games this season, 1.3 more points than the over/under in this contest.
• Northern Illinois' games have an average over/under of 161.2 points this season, 10.7 more points than the over/under for this game.

Betting the Spread: Loyola Chicago vs. Northern Illinois

• Loyola Chicago is winless against the spread this season.
• The Ramblers have yet to cover the spread this season when favored by 13.5 points or more.
• Northern Illinois has played four games, with three wins against the spread.
• The Huskies have covered the spread twice this year when underdogs by 13.5 points or more (in three chances).
• Loyola Chicago is winless against the spread, and 1-2 overall, at home this year.
• At home, as a 13.5-point favorite or more, Loyola Chicago is winless ATS (0-2).
• Northern Illinois has two wins against the spread, and are 0-3 overall, away from home.

Betting the Moneyline: Loyola Chicago vs. Northern Illinois

• Loyola Chicago has entered the game as moneyline favorites three times this season and won once.
• The Ramblers have played as a favorite of -1220 or more twice this season and split those games.
• The moneyline for this contest implies a 92.4% chance of a victory for Loyola Chicago.
• Northern Illinois has been moneyline underdogs in three games this season, however, it has failed to come away with a win in any of those games.
• The Huskies have won all of their three games in which they were named as at least a +744 moneyline underdog.
• The moneyline set for this matchup implies Northern Illinois has an 11.8% chance of walking away with the win.