Rams vs. Cardinals Week 14 Dunkel NFL Picks, Predictions and Odds

The Arizona Cardinals (3-9) will be aiming to snap a four-game losing run against the Los Angeles Rams (9-3). The Rams are solid favorites, expected to win by at least a touchdown (currently -9.5). The total for this one is set at 49.5 points.

The Rams are totaling 360.1 yards per game on offense, which ranks them eighth in the NFL. Defensively, they rank 13th, giving up 315.1 yards per game. With 337.3 total yards per game on the offensive side of the ball, the Cardinals rank 16th in the NFL in 2025. Defensively, they rank 19th, surrendering 332.2 total yards per game.

Rams vs. Cardinals Odds and Game Time

• Date: Sunday, December 7, 2025
• Time: 4:25 p.m. ET
• City: Glendale, Arizona
• Venue: State Farm Stadium
• Total: 49.5 points
• Spread: Rams -9.5
• Moneyline: Rams (-485), Cardinals (+370)

How to watch Rams vs. Cardinals

• TV Channel: FOX (KMSB-Tuscon, AZ)
• Live Stream: Fubo

Betting the Over/Under: Rams vs. Cardinals

• The Rams and their opponents have gone over 49.5 combined points in four of 12 games this season.
• Los Angeles and its opponent have combined to hit the over five out of 12 times this season.
• The Cardinals have played five games this season that finished with a point total higher than 49.5 points.
• In 2025, seven Arizona games have hit the over.
• The teams average 49.9 points per game combined, 0.4 more points than this game's total.
• These two teams allow a combined 42.8 points per game, 6.7 fewer points than this matchup's over/under.

Betting the Spread: Rams vs. Cardinals

• Los Angeles is 8-4-0 ATS this season.
• Los Angeles has been favored by 9.5 points or more two times this season, and covered the spread in one of those contests.
• The Cardinals have covered six times in 12 games with a spread this season.
• Arizona has covered the spread when playing as at least 9.5-point underdogs in its only opportunity this season.
• The Cardinals have covered the spread once at home, and are 1-5 overall there this season.
• This season away from home, the Rams are 4-2 against the spread and 4-2 overall.
• Los Angeles is winless ATS (0-1) as 9.5-point favorites or more on the road.

Betting the Moneyline: Rams vs. Cardinals

• Los Angeles has won 81.8% of the games this season when it was favored on the moneyline (9-2).
• The Cardinals have entered the game as underdogs nine times this season and won once.
• Los Angeles has played as a moneyline favorite of -485 or shorter in only two games this season, and it split 1-1.
• Arizona has not entered a game this season as a bigger underdog on the moneyline than the +370 odds on them winning this game.
• The implied moneyline probability for this matchup gives the Rams an 82.9% chance to win.

Dunkel Prediction for Rams vs. Cardinals

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