Jaguars vs. Colts Week 17 Dunkel NFL Picks, Predictions and Odds
23 December 2025

The Jacksonville Jaguars (11-4) are the favorites, expected to win by at least a field goal but less than a touchdown (currently -5.5) over the Indianapolis Colts (8-7). The Colts have lost five games straight. The total for this one is set at 48.5 points.
On offense, the Jaguars rank seventh in the NFL with 27.3 points per game. Meanwhile, they rank 11th in points allowed (317.6 points allowed per contest). From an offensive standpoint, the Colts are accumulating 27.9 points per game (sixth-ranked). They rank 18th in the NFL on defense (23.4 points surrendered per game).
Jaguars vs. Colts Odds and Game Time
- Date: Sunday, December 28, 2025
- Time: 1 p.m. ET
- City: Indianapolis, Indiana
- Venue: Lucas Oil Stadium
- Total: 48.5 points
- Spread: Jaguars -5.5
- Moneyline: Jaguars (-258), Colts (+210)
How to watch Jaguars vs. Colts
- TV Channel: FOX Net (Minot-Bismarck, ND)
- Live Stream: Fubo
Betting the Over/Under: Jaguars vs. Colts
- The Jaguars and their opponents have scored more than 48.5 points in eight of 15 games this season.
- Jacksonville games have gone over the point total nine out of 15 times this season.
- The Colts and their opponents have combined to score more than 48.5 points in eight of 15 games this season.
- So far this year, eight of Indianapolis' 15 games with a set number have hit the over.
- These teams score 55.2 points per game combined, 6.7 more than this game's total.
- These two teams surrender a combined 44.2 points per game, 4.3 fewer points than this contest's total.
Betting the Spread: Jaguars vs. Colts
- Jacksonville has won 10 games against the spread this season, while failing to cover five times.
- Jacksonville has won each of its two games this season when playing as at least 5.5-point favorites.
- The Colts have put together an 8-7-0 ATS record so far this year.
- Indianapolis has covered the spread when playing as at least 5.5-point underdogs in its only opportunity this season.
- The Colts are 6-2 overall, and 4-4 against the spread, at home.
- On the road, the Jaguars are 4-3 against the spread and 5-2 overall.
- Jacksonville is unbeaten ATS (1-0) as 5.5-point favorites or more away from home.
Betting the Moneyline: Jaguars vs. Colts
- Jacksonville has won 85.7% of the games this season when it was the moneyline favorite (6-1).
- The Colts have won two of the six games they've played as underdogs this season.
- Jacksonville has played as a moneyline favorite of -258 or shorter in just two games this season, and it won both.
- Indianapolis has played as an underdog of +210 or more once this season and lost that game.
- Based on this game's moneyline, the Jaguars have an implied win probability of 72.1%.
Dunkel Prediction for Jaguars vs. Colts
| ATS | Over/Under | Score Prediction |
|---|---|---|
| Jaguars (-5.5) | Under (48.5) | Jaguars 27 - Colts 15 |
For more expert NFL picks, visit our Dunkel Index NFL Picks and Predictions.
