Islanders vs. Blues NHL Predictions, Picks and Odds - Nov. 22
22 November 2025

The New York Islanders and St. Louis Blues are coming off a victory and a defeat, respectively, heading into their meeting at UBS Arena on Saturday at 3:30 p.m. ET. The Blues are underdogs away from home, at +110, and the Islanders are -130.
New York grabbed a 5-0 victory on the road its last time out on Nov. 20 against the Detroit Red Wings. Maxim Shabanov had three points (two goals and one assist) for the Islanders.
St. Louis played on the road in its last game on Nov. 20, and lost 3-2 in overtime against the Philadelphia Flyers. Justin Faulk led the Blues with two points (two goals) in that outing.
Ahead of watching this matchup, here is our pick for which club will take home the victory in Saturday's hockey action.
Bet now on FanDuel Sportsbook!Islanders vs. Blues Predictions & Pick
For the upcoming contest between the New York Islanders and St. Louis Blues, computer-calculated moneyline, over/under, and score predictions are below, sourced from Dunkel Index.
- Prediction: Islanders 5 - Blues 2
- Pick OU:
Over 6.5
(Dunkel projecting 7.06 goals)
Pick with the best in the business! Get free picks for every game, every week at the Dunkel Index.
Islanders vs. Blues Moneylines
Take a peek below at the latest moneylines for the Islanders-Blues matchup.
- Favorite: Islanders (-130)
- Underdog: Blues (+110)
Islanders Betting Insights
- The Islanders are 3-4 this season when listed as a moneyline favorite.
- New York is 2-4 when it has played with moneyline odds of -130 or shorter (33.3% win percentage).
- Based on this matchup's moneyline, the Islanders have an implied probability of 56.5% to win.
- New York's games this season have gone over this matchup's total of 6.5 goals 11 times.
Blues Betting Insights
- The Blues have been an underdog in eight games this season, and won four (50.0%).
- This season St. Louis has won one of its four games when it's the underdog by at least +110 on the moneyline.
- The moneyline for this contest implies a 47.6% chance of victory for the Blues.
- St. Louis' games this season have had more than 6.5 goals 10 of 21 times.
Islanders Key Stats
- New York's 69 total goals (3.3 per game) rank sixth in the league.
- The Islanders rank 16th in goals against, conceding 62 total goals (3.0 per game) in league play.
- It has the league's 10th-best goal differential at +7.
- The 10 power-play goals the Islanders have scored this season (on 70 power-play chances) rank 22nd in the NHL.
- New York has the league's 29th-ranked power-play conversion rate (14.29%).
- The five shorthanded goals the Islanders have scored this season are an NHL high.
- New York kills 82.61% of opponent power plays, the 11th-ranked penalty-kill percentage in the league.
- New York wins 51.9% of its faceoffs to rank 11th in the NHL.
- The Islanders have an 11.6% shooting percentage as a team, which ranks 10th in the league.
Blues Key Stats
- St. Louis has 57 goals this season (2.7 per game), 27th in the league.
- The Blues have allowed 79 total goals this season (3.8 per game), 30th in the NHL.
- it has the 31st-ranked goal differential in the league at -22.
- The Blues have 13 power-play goals (on 53 chances), 14th in the NHL.
- St. Louis scores on 24.53% of its power plays, No. 8 in the league.
- In terms of shorthanded goals, the Blues have two.
- The 73.58% penalty-kill percentage of St. Louis is 27th in the league.
- St. Louis wins 51% of faceoffs, 12th-ranked in the NHL.
- The 10.5% shooting percentage of the Blues is 21st in the league.
