Indiana vs. Siena Dunkel Predictions & Vegas Odds - Dec. 22

The Indiana Hoosiers (9-3) host the Siena Saints (9-3) at Simon Skjodt Assembly Hall, starting at 6 p.m. ET on Monday, December 22, 2025. The Hoosiers are 23.5-point favorites in the game. The matchup has an over/under of 141.5.

Indiana is coming off of a 78-58 victory over Chicago State in its most recent game on Saturday. Lamar Wilkerson's team-leading 21 points led Indiana in the win. Siena fell in its most recent matchup 83-69 against Vermont on Wednesday. Gavin Doty scored 18 points in Siena's loss, leading the team.

Indiana vs. Siena Odds and Game Time

• When: Monday, December 22, 2025 at 6 p.m. ET
• Where: Simon Skjodt Assembly Hall in Bloomington, Indiana
• Spread favorite: Indiana -23.5
• Moneyline favorite: Indiana -10000
• Moneyline underdog: Siena +2400
• Over/Under: 141.5 points

How to watch Indiana vs. Siena

• TV Channel: Big Ten Network
• Live Stream: Fubo
• Check out the rest of our Dunkel Index NCAA Basketball Picks!

Betting the Over/Under: Indiana vs. Siena

• Indiana and its opponents have combined to hit the over on Monday's total of 141.5 points seven times this season.
• In Siena's 12 games this season, three finished with more combined points than Monday's over/under of 141.5.
• The over/under for the game of 141.5 is 13.8 points fewer than the combined points per game averages for the Hoosiers (85.0 points per game) and the Saints (70.3 points per game).
• The 129.8 points per game these two teams allow their opponents to score combined this season are 11.7 less than the 141.5-point total in this contest.
• Indiana has a 151.6 average over/under in its games this season, 10.1 more points than the over/under in this contest.
• The over/under for this matchup is 8.0 points higher than the average over/under in Siena's games this season of 133.5.

Betting the Spread: Indiana vs. Siena

• Indiana is 6-6-0 against the spread this season.
• The Hoosiers have been favored by 23.5 points or more six times this season and are 3-3 ATS in those contests.
• Against the spread, Siena is 7-5-0 this year.
• Indiana is 5-3 against the spread, and 8-0 overall, at home this season.
• This season, as a 23.5-point favorite or greater at home, Indiana is 3-3 ATS.
• Away from home, Siena is 3-2 against the spread, and 3-2 overall.

Betting the Moneyline: Indiana vs. Siena

• This season, Indiana has won nine out of the 10 games in which it has been the moneyline favorite.
• The Hoosiers have entered four games this season favored by -10000 or more, and won each of those games.
• Indiana has a 99% chance to win this game based on the implied probability of the moneyline.
• Siena was defeated in both of the match ups it has played as moneyline underdogs this season.
• Oddsmakers have given the Saints the worst odds of winning they have seen this season with a +2400 moneyline listed for this contest.
• Siena has an implied victory probability of 4% according to the moneyline set by sportsbooks for this matchup.