Houston vs. Syracuse Dunkel Predictions & Vegas Odds - Nov. 24

The No. 2 Houston Cougars (5-0) visit the Syracuse Orange (4-0) at MGM Grand Garden Arena, beginning at 6 p.m. ET on Monday, November 24, 2025. The Orange are 10.5-point underdogs in the game. The over/under is set at 138.5 in the matchup.

Houston took care of business in its last outing 91-45 against Rider on Thursday. In the victory, Kingston Flemings led Houston with 18 points. Syracuse came out on top in its most recent outing 78-73 against Monmouth on Tuesday. Donnie Freeman put up 18 points, seven rebounds and three assists for Syracuse.

Houston vs. Syracuse Odds and Game Time

• When: Monday, November 24, 2025 at 6 p.m. ET
• Where: MGM Grand Garden Arena in Las Vegas, Nevada
• Spread favorite: Houston -10.5
• Over/Under: 138.5 points

How to watch Houston vs. Syracuse

• TV Channel: TNT
• Check out the rest of our Dunkel Index NCAA Basketball Picks!

Betting the Over/Under: Houston vs. Syracuse

• Houston played 11 games with more than 138.5 points scored, its current matchup's point total, last year.
• Last season, 24 of Syracuse's 33 matchups went over 138.5 total points scored.
• These teams averaged a combined 148.4 points per game a season ago, 9.9 more points than the over/under of 138.5 set for this game.
• Opponents of these two teams averaged a combined 136.5 points per game last season, 2.0 fewer than the point total in this game.
• The average point total for Houston's games last year was 6.2 fewer points than the total of 138.5 in this matchup.
• Syracuse's games in 2024 averaged an over/under of 152.4 points, 13.9 more than the point total in this matchup.

Betting the Spread: Houston vs. Syracuse

• Houston compiled a 21-19-0 ATS record last year.
• The Cougars had an ATS record of 11-11 when playing as at least 10.5-point favorites last season.
• Syracuse put together an 18-15-0 record against the spread last year.
• The Orange covered the spread six times last year (6-3 ATS) when playing as at least 10.5-point underdogs.
• Syracuse was 11-6 overall, and 9-8 against the spread, at home last year.
• Syracuse had one win ATS (1-4) as a 10.5-point underdog or more at home last year.
• Houston was 7-3 against the spread, and 10-0 overall, away from home last season.
• Houston went 3-2 ATS as a 10.5-point favorite or more on the road.