Astros vs. Guardians Dunkel MLB Picks, Predictions and Prop Bets - June 20

Jeremy Pena takes a two-game homer streak into the Houston Astros' game against the Cleveland Guardians at 7:15 p.m. ET on Saturday, at Daikin Park. Spencer Arrighetti (7-2, 2.57 ERA) will start for the Astros, who are 36-41 this season and fourth in the AL West. Joey Cantillo (5-3, 4.37 ERA) is the expected starter for the Guardians, who are 40-36 and second in the AL Central.

With the Guardians (+106) visiting, the Astros (-128) are a solid favorite on the moneyline. The game's total is set at 8.5.

Astros vs. Guardians Odds, Game Time

• Game day: Saturday, June 20, 2026
• Game time: 7:15 p.m. ET
• Location: Houston, Texas
• Stadium: Daikin Park
• Favorite: Astros (-128)
• Underdog: Guardians (+106)
• Over/under: 8.5

How to Watch Astros vs. Guardians

• TV Channel: FOX
• Live Stream: Fubo (Watch for free)

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Astros vs. Guardians: Betting the Moneyline

• The Astros have won 11 of the 26 games they were the moneyline favorite this season (42.3%).
• Cleveland has won in 19, or 52.8%, of the 36 contests it has been named as odds-on underdogs in this year.
• Houston has entered 18 games this season favored by -128 or more and is 8-10 in those contests.
• The Guardians have a win-loss record of 16-12 when favored by +106 or worse by oddsmakers this year.
• Based on this game's moneyline, the Astros have an implied win probability of 56.1%.
• The Guardians have an implied victory probability of 48.5% according to the moneyline set by oddsmakers for this matchup.

Astros vs. Guardians: Betting the Spread & Total

• The Astros have played in 77 games with over/under set, and have combined with opponents to go over the total 41 times (41-32-4).
• So far this season, Cleveland and its opponents have hit the over in 37 of its 76 games with a total.
• The Astros have a 37-40-0 record ATS this season (covering 48.1% of the time).
• In 76 games with a line this season, the Guardians have a mark of 39-37-0 against the spread.