Astros vs. White Sox Game 1 of the AL Wild Card Series Dunkel MLB Picks, Predictions and Props - Sept. 29

The AL Wild Card Series begins with a battle between the Houston Astros and Chicago White Sox, Tuesday at 5 p.m. ET, at Daikin Park. A.J. Blubaugh (5-3, 3.66 ERA) will start for the Astros, and Hagen Smith (3-3, 1.29 ERA) is expected to start for the White Sox.

The Astros (-125) are moneyline favorites at home over the White Sox (+104). The over/under for the Astros-White Sox game is 8.

Astros vs. White Sox Odds, Game Time

• Game day: Tuesday, September 29, 2026
• Game time: 5 p.m. ET
• Location: Houston, Texas
• Stadium: Daikin Park
• Favorite: Astros (-125)
• Underdog: White Sox (+104)
• Over/under: 8

How to Watch Astros vs. White Sox

• TV Channel: NBCSN and Peacock
• Live Stream: Fubo (Watch for free)

Bet now on FanDuel Sportsbook!

Astros vs. White Sox: Betting the Moneyline

• The Astros have compiled a 36-35 record in games they were favored on the moneyline (winning 50.7% of those games).
• Chicago has been victorious in 53, or 49.1%, of the 108 contests it has been chosen as underdogs in this season.
• Houston has a record of 29-27 in games when oddsmakers favor them by at least -125 on the moneyline.
• This season, the White Sox have come away with a win 42 times in 84 chances when named as an underdog of at least +104 or longer on the moneyline.
• The Astros have a 55.6% chance to win this game based on the moneyline's implied probability.
• Oddsmakers have implied with the moneyline set for this matchup that the White Sox have a 49% chance of pulling out a win.

Astros vs. White Sox: Betting the Spread & Total

• The Astros have had an over/under set by oddsmakers 162 times, and have combined with opponents to go over the total in 79 of those games (79-73-10).
• So far this season, Chicago and its opponents have hit the over in 93 of its 162 games with a total.
• The Astros have an 85-77-0 record against the spread this season (covering 52.5% of the time).
• In 162 games with a line this season, the White Sox have a mark of 93-69-0 against the spread.