Grand Canyon vs. IU Indianapolis Dunkel Predictions & Vegas Odds - Dec. 22

The Grand Canyon Antelopes (7-4) host the IU Indianapolis Jaguars (4-9) at Global Credit Union Arena, starting at 8 p.m. ET on Monday, December 22, 2025. The Antelopes are 25.5-point favorites in the game. The over/under is 169.5 in the matchup.

Their last time out, Grand Canyon won on Saturday 82-70 against Wyoming. Makaih Williams' team-high 20 points paced Grand Canyon in the victory. IU Indianapolis' most recent game on Tuesday ended in a 126-73 victory over Miami-Middletown. Jaxon Edwards totaled 19 points, three rebounds and four assists for IU Indianapolis.

Grand Canyon vs. IU Indianapolis Odds and Game Time

• When: Monday, December 22, 2025 at 8 p.m. ET
• Where: Global Credit Union Arena in Phoenix, Arizona
• Spread favorite: Grand Canyon -25.5
• Moneyline favorite: Grand Canyon -8333
• Moneyline underdog: IU Indianapolis +2600
• Over/Under: 169.5 points

How to watch Grand Canyon vs. IU Indianapolis

• TV Channel: MW Network
• Check out the rest of our Dunkel Index NCAA Basketball Picks!

Betting the Over/Under: Grand Canyon vs. IU Indianapolis

• This season, Grand Canyon's games have gone over this game's 169.5-point over/under just once.
• There have been eight IU Indianapolis games that finished with a combined score higher than 169.5 points this season.
• The Antelopes average 75.5 points per game and the Jaguars score 89.1, amounting to 4.9 points under the game's over/under of 169.5.
• The 159.7 points per game these two teams surrender to opponents on average this season are 9.8 fewer than the 169.5 total in this contest.
• This season the average over/under for Grand Canyon's games is 143.5 points, 26 fewer than the over/under of 169.5 set for this contest.
• A difference of 11.4 points separates the average over/under in IU Indianapolis' games (180.9 points) and this matchup's over/under (169.5).

Betting the Spread: Grand Canyon vs. IU Indianapolis

• Grand Canyon has five wins against the spread in 11 games this year.
• IU Indianapolis has three wins against the spread in 11 games this season.
• This season, the Jaguars won ATS in their only game as an underdog of 25.5 points or more.
• At home this year, Grand Canyon is 5-1 overall and 3-3 against the spread.
• IU Indianapolis has two wins against the spread, and are 1-5 overall, on the road.

Betting the Moneyline: Grand Canyon vs. IU Indianapolis

• Grand Canyon has entered the game as moneyline favorites seven times this season and won six of those games.
• The Antelopes have played as a favorite of -8333 or more once this season and won that game.
• The moneyline for this contest implies a 98.8% chance of a victory for Grand Canyon.
• IU Indianapolis has won in one of the six contests it has been named as the moneyline underdog this year.
• The Jaguars have played as an underdog of +2600 or more just one time this year and came away with a loss in that game.
• Sportsbooks have implied with the moneyline set for this matchup that IU Indianapolis has a 3.7% chance of pulling out a win.

Dunkel Index Prediction for Grand Canyon vs. IU Indianapolis

• Pick ATS: IU Indianapolis (+ 25.5)
• Pick OU: Over (169.5)
  
• Prediction: Grand Canyon 96 - IU Indianapolis 77