Duke vs. TCU Dunkel Predictions & Vegas Odds - Second Round

The No. 1 seed Duke Blue Devils (33-2) are 11.5-point favorites to advance to the Sweet 16 of the NCAA Tournament when they play the No. 9 seed TCU Horned Frogs (23-11) on Saturday at 5:15 p.m. ET on CBS. The matchup has an over/under set at 139.5 points.

Duke is coming off of a 71-65 victory over Siena in its most recent outing on Thursday. Cameron Boozer scored a team-leading 22 points for Duke in the victory. TCU is coming off of a 66-64 victory over Ohio State in its most recent outing on Thursday. Micah Robinson recorded 18 points, five rebounds and zero assists for TCU.

Duke vs. TCU Odds and Game Time

• When: Saturday, March 21, 2026 at 5:15 p.m. ET
• Where: Bon Secours Wellness Arena in Greenville, South Carolina
• Spread favorite: Duke -11.5
• Moneyline favorite: Duke -833
• Moneyline underdog: TCU +528
• Over/Under: 139.5 points

How to watch Duke vs. TCU

• TV Channel: CBS
• Check out the rest of our Dunkel Index NCAA Basketball Picks!

Betting the Over/Under: Duke vs. TCU

• A total of 19 of Duke's games this season have gone over Saturday's over/under of 139.5 points.
• There have been 20 TCU games that finished with a combined score higher than 139.5 points this season.
• Together, the two teams combine for 159.9 points per game, 20.4 points more than the total of 139.5 for this matchup.
• The 135 points per game these two teams surrender to opponents combined this season are 4.5 less than the 139.5-point over/under in this contest.
• Duke has seen a 145.2 average over/under in its games this season, 5.7 points more than the over/under in this matchup.
• The over/under for this matchup is 10.3 points lower than the average over/under in TCU's games this season of 149.8.

Betting the Spread: Duke vs. TCU

• Against the spread, Duke is 19-16-0 this year.
• The Blue Devils have an against the spread record of 9-12 in their 21 games when favored by 11.5 points or more so far this season.
• TCU has played 34 games, with 20 wins against the spread.
• This year, the Horned Frogs have won ATS in each of their two games as an underdog of 11.5 points or more.
• At home this year, Duke is 15-0 overall and 7-8 against the spread.
• As a 11.5-point favorite or greater at home, Duke is 5-7 ATS.
• In away games, TCU is 4-5 overall and 6-3 against the spread.

Betting the Moneyline: Duke vs. TCU

• Duke has won 29, or 93.5%, of the 31 games it has played as the moneyline favorite this season.
• The Blue Devils have entered 18 games this season favored by -833 or more, and won each of those games.
• The implied probability of a win from Duke, based on the moneyline, is 89.3%.
• TCU has been victorious in seven, or 53.8%, of the 13 contests it has been chosen as a moneyline underdog in this season.
• The Horned Frogs have been listed as an underdog of +528 or more on two occasions this season and split those games.
• The moneyline set for this matchup implies TCU has a 15.9% chance of walking away with the win.