Drexel vs. Pennsylvania Dunkel Predictions & Vegas Odds - Nov. 21

The Drexel Dragons (2-3) take on the Pennsylvania Quakers (2-2) as 5.5-point favorites on Friday, November 21, 2025 at 7 p.m. ET on FloCollege. The point total in the matchup is set at 153.5.

Last time out, Drexel won on Tuesday 75-43 over NJIT. In the win, Kevon Vanderhorst paced Drexel with 13 points. Pennsylvania won its last outing 83-74 against Saint Joseph's (PA) on Monday. Ethan Roberts scored a team-best 31 points for Pennsylvania in the win.

Drexel vs. Pennsylvania Odds and Game Time

• When: Friday, November 21, 2025 at 7 p.m. ET
• Where: Daskalakis Athletic Center in Philadelphia, Pennsylvania
• Spread favorite: Drexel -5.5
• Moneyline favorite: Drexel -238
• Moneyline underdog: Pennsylvania +195
• Over/Under: 153.5 points

How to watch Drexel vs. Pennsylvania

• TV Channel: NBC Sports Philadelphia
• Live Stream: Fubo
• Check out the rest of our Dunkel Index NCAA Basketball Picks!

Betting the Over/Under: Drexel vs. Pennsylvania

• Drexel's games went over 153.5 points scored, its current matchup's over/under, six times (out of 31) last season.
• Pennsylvania's games went over 153.5 total points scored in 11 of 27 matchups last season.
• These teams averaged a combined 140 points per game a season ago, 13.5 fewer points than the over/under of 153.5 set for this game.
• Opponents of these two teams averaged a combined 144.3 points per game last season, 9.2 fewer than the point total for this game.
• Drexel's average point total in matchups last year was 137.2, 16.3 points below the total in this game.
• The average total for Pennsylvania's games in 2024 was 6.5 fewer points than the point total of 153.5 for this game.

Betting the Spread: Drexel vs. Pennsylvania

• Drexel went 19-11-1 ATS last season.
• The Dragons covered the spread once last season (1-1 ATS) when playing as at least 5.5-point favorites.
• Pennsylvania won 11 games against the spread last year, while failing to cover 16 times.
• The Quakers were 5-7 ATS last season when playing as at least 5.5-point underdogs.
• Drexel was 7-5 overall, and 7-4-1 against the spread, at home last season.
• At home last year, Drexel was unbeaten ATS (1-0) as a 5.5-point favorite or more.
• Away from home last season, Pennsylvania was 6-7 against the spread and 3-10 overall.
• Pennsylvania was winless ATS (0-1) as a 5.5-point underdog or more on the road.

Betting the Moneyline: Drexel vs. Pennsylvania

• Drexel finished 11-6 in games it was listed as the moneyline favorite last season (winning 64.7% of those games).
• The Dragons played as a moneyline favorite of -238 or shorter in only one game last season, which they won.
• Based on this matchup's moneyline, Drexel has an implied win probability of 70.4%.
• Pennsylvania was underdogs in 19 games last season and won four (21.1%) of those contests.
• The Quakers had a record of 1-11 in games where sportsbooks had them as underdogs of at least +195 on the moneyline.
• Sportsbooks have implied with the moneyline set for this matchup that Pennsylvania has a 33.9% chance to win.