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Tigers vs. Nationals Dunkel MLB Picks, Predictions and Prop Bets - Sept. 22

22 September 2026 By Data Skrive

C.J. Abrams is only one RBI away from his 100th of the campaign as his Washington Nationals face the Detroit Tigers on Tuesday at 6:40 p.m. ET. Drew Anderson (5-6, 3.62 ERA) will start for the Tigers, who are 74-83 this season and third in the AL Central. Riley Cornelio (3-2, 4.22 ERA) is starting for the Nationals, who are 73-84 and fourth in the NL East.

The Nationals (+131) are on the road versus the favored Tigers (-159). The total for the Tigers-Nationals game is set at 8.

Tigers vs. Nationals Odds, Game Time

  • Game day: Tuesday, September 22, 2026
  • Game time: 6:40 p.m. ET
  • Location: Detroit, Michigan
  • Stadium: Comerica Park
  • Favorite: Tigers (-159)
  • Underdog: Nationals (+131)
  • Over/under: 8

How to Watch Tigers vs. Nationals

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Tigers vs. Nationals: Betting the Moneyline

  • The Tigers have won 45 of the 83 games they were the moneyline favorite this season (54.2%).
  • Washington has been underdogs in 120 games this season and has come away with the win 50 times (41.7%) in those contests.
  • Detroit has a record of 13-5, a 72.2% win rate, when favored by -159 or more by oddsmakers this season.
  • This season, the Nationals have come away with a win 18 times in 58 chances when named as an underdog of at least +131 or worse on the moneyline.
  • Based on this contest's moneyline, the Tigers' implied win probability is 61.4%.
  • The moneyline set for this matchup implies the Nationals have a 43.3% chance of coming away with a victory in the contest.

Tigers vs. Nationals: Betting the Spread & Total

  • The Tigers have combined with opponents to hit the over on the total 69 times this season for a 69-80-8 record against the over/under.
  • So far this season, Washington and its opponents have hit the over in 83 of its 157 games with a total.
  • The Tigers have covered 52.2% of their games this season, going 82-75-0 against the spread.
  • The Nationals are 87-70-0 against the spread in their 157 games that had a posted line this season.
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